Saints vs. Lions: NFL Week 1 Prediction, Picks & Odds

Dimers' Saints vs. Lions prediction for Sunday, September 13, 2026. Win probabilities, projected final score, current odds, and picks from our NFL machine learning models.
FINAL
NFL
FINAL
NFL sport icon
NFL
Saints
30
31
Ford Field
Lions
Ford Field
Live Probabilities
Win %
  • Saints
    0%
  • Lions
    100%
Win Probability
TEAM1234OTT
Saints
0 0 14 10 6 30
Lions
7 0 14 3 7 31
1 0 2 0 3 0 4 0 5 0 4 0 3 0 2 0 1 0 1 0 2 0 3 0 4 0 5 0 4 0 3 0 2 0 1 0
Lions
Saints
1st and 10 at the NO 48
Last Play
End Game

Saints vs. Lions: Detailed Breakdown

Matchup overview: NFL Week 1

  • Teams: New Orleans Saints vs. Detroit Lions
  • Date: Sunday, September 13, 2026
  • Time: 1:00PM ET
  • Venue: Ford Field

Current betting odds

  • Spread: Saints (+6.5, +108), Lions (-6.5, -115)
  • Moneyline: Saints +285, Lions -285
  • Total (Over/Under): 50.5 points (+102/-108)

Dimers’ win probabilities

  • Saints: 27.1%
  • Lions: 72.9%

These probabilities come from two machine learning models that assess more than 100 data points for each NFL matchup, combining their outputs to project all our major betting markets.

Projected final score

Our predicted final score for this NFL matchup is Saints 21-28 Lions.

This prediction draws on each team's scoring trends and player stats, weighed across both of our data models.

Our Prediction: Who Wins?

The numbers give the Saints a win probability of 27.1%, while the Lions have a win probability of 72.9%.

Summary

The Saints face off against the Lions in the NFL at Ford Field on Sunday, September 13, 2026.

Our Saints vs. Lions predictions, built on real-time data and matchup-specific modeling, help guide your decisions.. Remember to bet responsibly and within your financial limits.

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For further insights, explore our expert NFL predictions and the best NFL bets today, while our in-depth analysis includes NFL props, NFL futures, NFL odds, and the latest NFL news.