Los Angeles Chargers vs. Seattle Seahawks: Experts release early Week 4 predictions [2026]

The Los Angeles Chargers and Seattle Seahawks will meet in Week 4 of the NFL season at Lumen Field on Sunday, October 4, 2026, starting at 4:25 PM ET.

Initial simulations from Dimers' trusted NFL model favor the Seahawks as the most likely winner of this cross-conference battle.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Chargers vs. Seahawks predictions page.

LA Chargers vs. Seattle early predictions

Leveraging trusted machine learning and analysis, we have simulated the Chargers vs. Seahawks game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Chargers 26.6%, Seahawks 73.4%
• Predicted final score: Chargers 18-25 Seahawks
• Spread: Chargers (+6.5) 46.8%, Seahawks (-6.5) 53.2%
• Total points (43.5): Over 50.0%, Under 50.0%

As of September 28, 2026, these Chargers-Seahawks calculations and predictions reflect the latest data and insights available.

Chargers vs. Seahawks Week 4 details

Sunday's game between the Seahawks and Chargers at Lumen Field is scheduled for October 4, 2026.

• Who: Los Angeles Chargers vs. Seattle Seahawks
• Date: Sunday, October 4, 2026
• Time: 4:25 PM ET/1:25PM PT
• Venue: Lumen Field

Chargers vs. Seahawks opening odds

We've researched the best betting odds across America for this Week 4 game, which are listed here:

• Spread: Chargers +6.5 (+113), Seahawks -6.5 (-110)
• Moneyline: Chargers +285, Seahawks -285
• Total: Over/Under 43.5 (+104/-105)

Odds may continue to move—track live changes via our NFL odds page.

NFL Week 4 promo

Using our full NFL Week 3 promo code guide, you can make the most of Dimers' Chargers vs. Seahawks predictions with the below DraftKings Sportsbook offer:

Conclusion

We predict the Seahawks, with a 73.4% win probability, will likely beat the Chargers in Week 4 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Chargers vs. Seahawks game, with human oversight maintaining high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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