49ers vs. Giants: NFL Week 13 Prediction, Picks & Odds
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- 49ers
- Giants
49ers vs. Giants: Detailed Breakdown
Matchup overview: NFL Week 13
- Teams: San Francisco 49ers vs. New York Giants
- Date: Sunday, December 6, 2026
- Time: 1:00PM ET
- Venue: MetLife Stadium
Current betting odds
- Spread: 49ers (-3, -115), Giants (+3, -115)
- Moneyline: 49ers -170, Giants +135
- Total (Over/Under): 48 points (-115/-115)
Dimers’ win probabilities
- 49ers: 63.1%
- Giants: 36.9%
These probabilities come from two machine learning models that assess more than 100 data points for each NFL matchup, combining their outputs to project all our major betting markets.
Projected final score
Our predicted final score for this NFL matchup is 49ers 25-22 Giants.
This prediction draws on each team's scoring trends and player stats, weighed across both of our data models
Our Prediction: Who Wins?
The numbers give the 49ers a win probability of 63.1%, while the Giants have a win probability of 36.9%.
Summary
The 49ers face off against the Giants in the NFL at MetLife Stadium on Sunday, December 6, 2026.
Our 49ers vs. Giants predictions, built on real-time data and matchup-specific modeling, help guide your decisions. Remember to bet responsibly and within your financial limits.
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