...
...
Read Article
- More Betting
Western Kentucky vs. LSU prediction: LSU favored to win in college football Week 13, 2025
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Western Kentucky vs LSU predictions for college football Saturday.
LSU will face Western Kentucky in Week 13 college football action at Tiger Stadium on Saturday, starting at 7:45PM ET.
Based on updated simulations, Dimers' advanced college football model predicts LSU as the most likely winner of the Western Kentucky vs. LSU game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Western Kentucky vs. LSU prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the outcome of Western Kentucky vs. LSU 10,000 times as part of our college football predictions coverage.
Our leading predictive model gives LSU a 95% chance of defeating Western Kentucky. Our predicted final score has LSU winning 37-13.
According to our model, the bookmakers have got it right, and Western Kentucky and LSU each have a 50% chance of covering the spread, while the over/under total of 52.5 points has a 53% chance of going over.
Western Kentucky vs. LSU odds
We have sourced the best College Football odds in America for this game, which are listed here:
| Bet Type | Western Kentucky | LSU |
|---|---|---|
| Spread | +24.5 (-105) | -24.5 (-110) |
| Moneyline | +1500 | -3200 |
| Total | o52.5 (-105) | u52.5 (-115) |
All odds are correct at the time of publication and are subject to change.
Western Kentucky vs. LSU picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Western Kentucky +24.5 | -105 |
| Moneyline | Western Kentucky | +1500 |
| Total | Over 52.5 | -105 |
According to our college football best bets, the top play to make on this game is Over 52.5 total points.
Western Kentucky vs. LSU game-day updates and essential details
Saturday's college football matchup between LSU and Western Kentucky at Tiger Stadium is scheduled to start at 7:45PM ET.
- Who: Western Kentucky vs. LSU
- Date: Saturday, November 22, 2025
- Time: 7:45PM ET/4:45PM PT
- Venue: Tiger Stadium
Sports betting deal available for Missouri sports fans
To make the most of the upcoming Missouri launch, check out details on the latest Bet365 bonus code "DIMERS" that unlocks $365 in bonus bets from a $10 bet — win or lose. Don't miss out!
Conclusion
We predict LSU, with a 95% win probability, will likely beat Western Kentucky on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Western Kentucky vs. LSU insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
Advertiser disclosure