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Wake Forest vs. Duke prediction: Duke favored to win in college football Week 14, 2025
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Wake Forest vs Duke predictions for college football Saturday.
Duke and Wake Forest will clash in Week 14 college football action at Brooks Field at Wallace Wade Stadium on Saturday, beginning at 3:30PM ET.
Based on updated simulation results, Dimers' advanced college football model predicts Duke as the most likely winner of the Wake Forest vs. Duke game.
This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Wake Forest vs. Duke prediction: Who will win and cover?
Using trusted machine learning and data analysis, we have simulated the outcome of Wake Forest vs. Duke 10,000 times as part of our college football predictions coverage.
Our leading predictive model currently gives Duke a 61% chance of defeating Wake Forest. Our predicted final score has Duke winning 28-24.
According to our model, Duke (-2.5) has a 59% chance of covering the spread, while the 53.5-point over/under has a 54% chance of going over.
Wake Forest vs. Duke odds
We have researched the best college football odds in America for this game, which are listed here:
| Bet Type | Wake Forest | Duke |
|---|---|---|
| Spread | +2.5 (-112) | -2.5 (-106) |
| Moneyline | +110 | -122 |
| Total | o53.5 (-110) | u53.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Wake Forest vs. Duke picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Duke -2.5 | -106 |
| Moneyline | Duke | -122 |
| Total | Over 53.5 | -110 |
According to our college football best bets, the top play to make on this game is Duke -2.5 at the spread.
Wake Forest vs. Duke game-day updates and essential details
Saturday's college football game between Duke and Wake Forest at Brooks Field at Wallace Wade Stadium is scheduled to begin at 3:30PM ET.
- Who: Wake Forest vs. Duke
- Date: Saturday, November 29, 2025
- Time: 3:30PM ET/12:30PM PT
- Venue: Brooks Field at Wallace Wade Stadium
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Conclusion
We predict Duke, with a 61% win probability, will likely beat Wake Forest on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Wake Forest vs. Duke insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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