CFB- More Betting
Tennessee State vs. Charleston Southern prediction: Why Charleston Southern is favored to win in college football Week 13, 2025
Get Tennessee State vs Charleston Southern predictions for college football Saturday.

Charleston Southern and Tennessee State will meet in Week 13 college football action at Buccaneer Field on Saturday, beginning at 2:00PM ET.
Based on the latest simulations, Dimers' advanced college football model projects Charleston Southern as the most likely winner of the Tennessee State vs. Charleston Southern game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Tennessee State vs. Charleston Southern prediction: Who will win and cover?
Using trusted machine learning and statistical analysis, we have simulated the outcome of Tennessee State vs. Charleston Southern 10,000 times as part of our college football predictions coverage.
Our famous predictive model currently gives Charleston Southern a 73% chance of defeating Tennessee State. Our predicted final score has Charleston Southern winning 26-18.
According to our model, Tennessee State (+11.5) has a 58% chance of covering the spread, while the over/under total of 43.5 points has a 57% chance of staying under.
Tennessee State vs. Charleston Southern odds
We have researched the best College Football odds in America for this game, which are listed here:
| Bet Type | Tennessee State | Charleston Southern |
|---|---|---|
| Spread | +11.5 (-110) | -11.5 (-110) |
| Moneyline | +455 | -530 |
| Total | o43.5 (-110) | u43.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Tennessee State vs. Charleston Southern picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Tennessee State +11.5 | -110 |
| Moneyline | Tennessee State | +455 |
| Total | Under 43.5 | -110 |
According to our college football best bets, the top play to make on this game is Tennessee State to win.
Tennessee State vs. Charleston Southern game-day updates and essential details
Saturday's college football game between Charleston Southern and Tennessee State at Buccaneer Field is scheduled to start at 2:00PM ET.
- Who: Tennessee State vs. Charleston Southern
- Date: Saturday, November 22, 2025
- Time: 2:00PM ET/11:00AM PT
- Venue: Buccaneer Field
Sports betting deal available for Missouri sports fans
To make the most of the upcoming Missouri launch, check out details on the latest Bet365 bonus code "DIMERS" that secures $365 in bonus bets from a $10 bet — win or lose. Don't miss out!
Conclusion
We predict Charleston Southern, with a 73% win probability, will likely beat Tennessee State on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Tennessee State vs. Charleston Southern insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
