St Louis City vs. San Jose Earthquakes prediction, odds, MLS picks [4/25/2026]
Get St Louis City vs San Jose Earthquakes predictions for MLS Saturday.

St Louis City will face San Jose in MLS action at CITYPARK on Saturday, starting at 8:30 PM ET.
Based on updated simulations, Dimers' advanced MLS model predicts St Louis City as the most likely winner of the St Louis City vs. San Jose game.
This article offers an expanded analysis of Saturday's match, including best bets and picks.
St Louis City vs. San Jose Earthquakes prediction: Who will win?
Using innovative machine learning and data, we have simulated the outcome of Saturday's MLS game between St Louis City and San Jose, forming part of our MLS predictions coverage.
Our leading predictive model currently indicates a 42.2% chance of St Louis City winning, a 34.1% chance for San Jose, and a 23.8% chance of a draw.
St Louis City vs. San Jose Earthquakes odds
We have researched the best MLS odds in America for this game, which are listed here:
| Market | St Louis City | San Jose | Draw |
|---|---|---|---|
| Moneyline | +110 | +220 | +300 |
All odds are correct at the time of publication and are subject to change.
St Louis City vs. San Jose Earthquakes picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | San Jose | +220 |
According to our best MLS bets, the top play to make on this game is San Jose to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
St Louis City vs. San Jose Earthquakes: Correct score predictions
The top three most likely final scores, according to our model, are listed below, with a 1-1 draw being the most probable:
| Final Score | Probability |
|---|---|
| STL 1-1 SJE | 10.8% |
| STL 2-1 SJE | 8.9% |
| STL 1-2 SJE | 7.9% |
These predictions are based on each team's average score according to our machine learning model, which means the most likely correct score may differ from our predicted winner.
St Louis City vs. San Jose Earthquakes game-day updates and essential details
Saturday's matchup between St Louis City and San Jose in MLS at CITYPARK is scheduled to start at 8:30 PM ET.
- Who: St Louis City vs. San Jose Earthquakes
- Date: Saturday, April 25, 2026
- Time: 8:30 PM ET/5:30PM PT
- Venue: CITYPARK
Conclusion
According to our computer model, St Louis City has a 42.2% win probability on Saturday, San Jose has a 34.1% win probability, and there is a 23.8% chance that the game will end in a draw.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.



