Southeast Missouri State vs. Gardner-Webb prediction: Gardner-Webb favored to win in college football Week 11, 2025

Gardner-Webb and Southeast Missouri State will clash in Week 11 college football action at Ernest W. Spangler Stadium on Saturday, with kickoff at 1:30PM ET.

Based on updated simulation results, Dimers' advanced college football model projects Gardner-Webb as the most likely winner of the Southeast Missouri State vs. Gardner-Webb game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Southeast Missouri State vs. Gardner-Webb prediction: Who will win, cover the spread?

Using innovative machine learning and data, we have simulated the result of Southeast Missouri State vs. Gardner-Webb 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Gardner-Webb a 64% chance of defeating Southeast Missouri State. Our predicted final score has Gardner-Webb winning 30-25.

According to our model, Gardner-Webb (-4.5) has a 52% chance of covering the spread, while the over/under total of 56.5 points has a 54% chance of going over.

Southeast Missouri State vs. Gardner-Webb odds

We have sourced the best College Football odds in America for this game, which are listed here:

Bet Type	Southeast Missouri State	Gardner-Webb
Spread	+4.5 (-110)	-4.5 (-110)
Moneyline	+158	-175
Total	o56.5 (-110)	u56.5 (-110)

All odds are correct at the time of publication and are subject to change.

Southeast Missouri State vs. Gardner-Webb picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Gardner-Webb -4.5	-110
Moneyline	Gardner-Webb	-175
Total	Over 56.5	-110

According to our college football best bets, the top play to make on this game is Over 56.5 total points.

Southeast Missouri State vs. Gardner-Webb game-day updates and essential details

Saturday's college football game between Gardner-Webb and Southeast Missouri State at Ernest W. Spangler Stadium is scheduled to start at 1:30PM ET.

• Who: Southeast Missouri State vs. Gardner-Webb
• Date: Saturday, November 8, 2025
• Time: 1:30PM ET/10:30AM PT
• Venue: Ernest W. Spangler Stadium

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Conclusion

We predict Gardner-Webb, with a 64% win probability, will likely beat Southeast Missouri State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Southeast Missouri State vs. Gardner-Webb insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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