South Carolina State vs. North Carolina Central prediction: North Carolina Central favored to win in college football Week 12, 2025

North Carolina Central and South Carolina State will lock horns in Week 12 college football action at O'Kelly-Riddick Stadium on Friday, starting at 5:30PM ET.

Based on updated simulation results, Dimers' proven college football model predicts North Carolina Central as the most likely winner of the South Carolina State vs. North Carolina Central game.

This article offers a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and picks.

South Carolina State vs. North Carolina Central prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of South Carolina State vs. North Carolina Central 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives North Carolina Central a 61% chance of beating South Carolina State. Our predicted final score has North Carolina Central winning 29-25.

According to our model, South Carolina State (+6.5) has a 55% chance of covering the spread, while the 55.5-point over/under has an equal 50-50 chance of hitting.

South Carolina State vs. North Carolina Central odds

We have researched the best College Football odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

South Carolina State vs. North Carolina Central picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our college football best bets, the top play to make on this game is South Carolina State to win.

South Carolina State vs. North Carolina Central game-day updates and essential details

Friday's college football game between North Carolina Central and South Carolina State at O'Kelly-Riddick Stadium is scheduled to start at 5:30PM ET.

• Who: South Carolina State vs. North Carolina Central
• Date: Friday, November 14, 2025
• Time: 5:30PM ET/2:30PM PT
• Venue: O'Kelly-Riddick Stadium

Conclusion

We predict North Carolina Central, with a 61% win probability, will likely beat South Carolina State on Friday.

AI and automation have enhanced this article to quickly deliver accurate South Carolina State vs. North Carolina Central insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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