Spurs vs. Raptors prediction: San Antonio to win, Victor Wembanyama projected for big game in Wednesday's NBA matchup [2/25/2026]

The Toronto Raptors will face the favored San Antonio Spurs in NBA action at Scotiabank Arena on Wednesday, beginning at 7:30 PM ET.

Based on the latest simulation results and today’s injury reports, Dimers' proven NBA model predicts the Spurs as the most likely winner of the Spurs vs. Raptors game.

This prediction follows the latest NBA Injury Report, which suggests the Raptors lineup will feature players like Brandon Ingram, Scottie Barnes and RJ Barrett, while the Spurs will rely on Victor Wembanyama, De'Aaron Fox and Stephon Castle.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Spurs vs. Raptors prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's NBA matchup between the Spurs and Raptors 10,000 times as part of our NBA predictions coverage.

Our independent predictive model currently gives the Spurs a 66% chance of beating the Raptors. Our predicted final score has the Spurs winning 117-112.

According to our model, the Raptors (+5.5) have a 53% chance of covering the spread, while the over/under total of 231.5 points has a 52% chance of staying under.

Spurs vs. Raptors odds

We have researched the best NBA odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Spurs vs. Raptors picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best NBA bets for Wednesday, the top play to make on this game is Raptors +5.5 at the spread.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

Spurs vs. Raptors player props

Looking for San Antonio vs. Toronto NBA prop bets? We have crunched the numbers to project how each team's leading players will perform at Scotiabank Arena.

Victor Wembanyama is expected to lead the Spurs with 24 points, 12 rebounds and 3 assists, while Brandon Ingram is projected to have 22 points, 5 rebounds and 4 assists for the Raptors.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and today's NBA first basket picks.

Spurs prediction

Our model's projected player stats for the Spurs are:

Raptors prediction

Projected points, rebounds, assists and three-pointers made for the Raptors:

Spurs vs. Raptors game-day updates and essential details

Wednesday's game between the Raptors and Spurs at Scotiabank Arena is scheduled to begin at 7:30 PM ET.

• Who: San Antonio Spurs vs. Toronto Raptors
• Date: Wednesday, February 25, 2026
• Time: 7:30 PM ET/4:30PM PT
• Venue: Scotiabank Arena

Conclusion

We predict the Spurs, with a 66% win probability, will likely beat the Raptors on Wednesday, with Victor Wembanyama projected for a game-high 54 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Spurs vs. Raptors insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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