Spurs vs. Trail Blazers prediction: Why Portland is favored to win Wednesday's NBA Cup game [11/26/2025]

NBA Cup action continues on Wednesday at 10:00PM ET as the San Antonio Spurs square off with the Portland Trail Blazers at Moda Center.

Based on the latest simulations and today’s injury updates, Dimers' proven NBA model projects the Trail Blazers as the most likely winner of the Spurs vs. Trail Blazers game.

This prediction follows the latest NBA Injury Report, which suggests the Trail Blazers lineup will feature players like Deni Avdija, Shaedon Sharpe and Jerami Grant, while the Spurs will rely on De'Aaron Fox, Devin Vassell and Harrison Barnes.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and player prop picks.

Spurs vs. Blazers prediction: Who will win NBA Cup game?

Using powerful machine learning and data, we have simulated the result of Wednesday's NBA game between the Spurs and Trail Blazers 10,000 times as part of our NBA predictions coverage.

Our independent predictive model gives the Trail Blazers a 57% chance of beating the Spurs. Our predicted final score has the Trail Blazers winning 119-117.

According to our model, the Trail Blazers (-1.5) have a 51% chance of covering the spread, while the 239.5-point over/under has a 54% chance of staying under.

Spurs vs. Trail Blazers odds

We have researched the best NBA odds in America for this game, which are listed here:

Bet Type	Spurs	Trail Blazers
Spread	+1.5 (-110)	-1.5 (+100)
Moneyline	+102	-115
Total	o239.5 (-110)	u239.5 (-108)

All odds are correct at the time of publication and are subject to change.

Spurs vs. Trail Blazers picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Trail Blazers -1.5	+100
Moneyline	Trail Blazers	-115
Total	Under 239.5	-108

According to our NBA best bets, the top play to make on this game is Trail Blazers to win.

Spurs vs. Trail Blazers player props

NBA player props are an exciting way to wager on Wednesday's San Antonio vs. Portland game without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Moda Center.

De'Aaron Fox is expected to lead the Spurs with 23 points, 4 rebounds and 6 assists, while Deni Avdija is projected to have 26 points, 7 rebounds and 6 assists for the Trail Blazers.

Check out our NBA player projections for a full range of projected box scores, including points, assists, rebounds and more, for every game this season.

Spurs prediction

Our model's projected player stats for the Spurs are:

Player	PTS	REB	AST	3PM	DFS
De'Aaron Fox	23	4	6	2	45
Devin Vassell	16	4	3	2	32
Harrison Barnes	15	4	2	2	28
Keldon Johnson	14	6	2	1	28
J. Champagnie	12	5	2	2	27

Trail Blazers prediction

Projected points, rebounds, assists and three-pointers made for the Trail Blazers:

Player	PTS	REB	AST	3PM	DFS
Deni Avdija	26	7	6	3	50
Shaedon Sharpe	20	5	3	2	36
Jerami Grant	17	3	3	2	30
Toumani Camara	13	5	3	2	30
Donovan Clingan	11	10	2	1	33

Spurs vs. Blazers game-day updates and essential details

Wednesday's matchup between the Trail Blazers and Spurs at Moda Center is scheduled to begin at 10:00PM ET.

• Who: San Antonio Spurs vs. Portland Trail Blazers
• Date: Wednesday, November 26, 2025
• Time: 10:00PM ET/7:00PM PT
• Venue: Moda Center
• Tournament details: 2025 Emirates NBA Cup

Conclusion

We predict the Trail Blazers, with a 57% win probability, will likely beat the Spurs on Wednesday, with Deni Avdija projected for a game-high 50 fantasy points.

AI and automation have enhanced this article to quickly deliver accurate Spurs vs. Trail Blazers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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