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Sam Houston State vs. Middle Tennessee prediction: Why Middle Tennessee is favored to win in college football Week 13, 2025

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Written by Mac Douglass

Get Sam Houston State vs Middle Tennessee predictions for college football Saturday.

Sam Houston State-Middle Tennessee Predictions and Game Preview.
Sam Houston State vs. Middle Tennessee college football gameday prediction for Saturday, November 22, 2025.

Middle Tennessee and Sam Houston State will meet in Week 13 college football action at Johnny "Red" Floyd Stadium on Saturday, starting at 3:00PM ET.

Based on updated simulations, Dimers' proven college football model predicts Middle Tennessee as the most likely winner of the Sam Houston State vs. Middle Tennessee game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Sam Houston State vs. Middle Tennessee prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Sam Houston State vs. Middle Tennessee 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Middle Tennessee a 59% chance of beating Sam Houston State. Our predicted final score has Middle Tennessee winning 29-25.

According to our model, Sam Houston State (+6.5) has a 57% chance of covering the spread, while the over/under total of 53.5 points has a 54% chance of staying under.

 

Sam Houston State vs. Middle Tennessee odds

We have researched the best College Football odds in America for this game, which are listed here:

Bet Type Sam Houston State Middle Tennessee
Spread +6.5 (-104) -6.5 (-115)
Moneyline +200 -245
Total o53.5 (-108) u53.5 (-105)

All odds are correct at the time of publication and are subject to change.

Sam Houston State vs. Middle Tennessee picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Sam Houston State +6.5 -104
Moneyline Sam Houston State +200
Total Under 53.5 -105

According to our best college football bets, the top play to make on this game is Sam Houston State to win.

 

Sam Houston State vs. Middle Tennessee game-day updates and essential details

Saturday's college football action between Middle Tennessee and Sam Houston State at Johnny "Red" Floyd Stadium is scheduled to start at 3:00PM ET.

  • Who: Sam Houston State vs. Middle Tennessee
  • Date: Saturday, November 22, 2025
  • Time: 3:00PM ET/12:00PM PT
  • Venue: Johnny "Red" Floyd Stadium

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Conclusion

We predict Middle Tennessee, with a 59% win probability, will likely beat Sam Houston State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Sam Houston State vs. Middle Tennessee insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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