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Pirates vs. Cubs prediction: Why Cubs are favored to win Sunday's MLB matchup [4/12/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Pittsburgh Pirates vs Chicago Cubs predictions for MLB Sunday.
The Chicago Cubs will face the Pittsburgh Pirates in MLB action at Wrigley Field on Sunday, beginning at 2:20 PM ET.
Jameson Taillon (0-1, 2.53 ERA) will start on the mound for the Cubs, up against Bubba Chandler (0-1, 3.12 ERA) for the Pirates.
Based on updated simulation results, Dimers' proven MLB model predicts the Cubs as the most likely winner of the Pirates vs. Cubs game.
This article offers further insights into Sunday's matchup, including best bets and picks.
Pirates vs. Cubs prediction: Who will win and cover?
Using powerful machine learning and statistical analysis, we have simulated the outcome of Sunday's MLB game between the Pirates and Cubs, forming part of our MLB predictions coverage.
Our leading predictive model currently gives the Cubs a 57% chance of defeating the Pirates.
According to our model, the Pirates (+1.5) have a 58% chance of covering the run line, while the 13.5-run over/under has a 59% chance of staying under.
Pirates vs. Cubs odds [4/12/2026]
We have researched the best MLB odds in America for this game, which are listed here:
| Bet Type | Pirates | Cubs |
|---|---|---|
| Run Line | +1.5 (-170) | -1.5 (+140) |
| Moneyline | +110 | +106 |
| Total | o13.5 (-102) | u13.5 (-114) |
All odds are correct at the time of publication and are subject to change.
Pirates vs. Cubs picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Cubs -1.5 | +140 |
| Moneyline | Cubs | +106 |
| Total | Under 13.5 | -114 |
According to our best MLB bets, the top play to make on this game is Cubs to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Pirates vs. Cubs game-day updates and essential details
Sunday's MLB game between the Cubs and Pirates at Wrigley Field is scheduled to commence at 2:20 PM ET.
- Who: Pittsburgh Pirates vs. Chicago Cubs
- Date: Sunday, April 12, 2026
- Time: 2:20 PM ET/11:20AM PT
- Venue: Wrigley Field
Conclusion
We predict the Cubs, with a 57% win probability, will likely beat the Pirates in Sunday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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