Penn State vs. Iowa prediction: Why Iowa is favored to win in college football Week 8, 2025

Iowa will square off with Penn State in Week 8 college football action at Kinnick Stadium on Saturday, starting at 7:00PM ET.

Based on the latest simulations, Dimers' advanced college football model predicts the Iowa as the most likely winner of today's game.

For further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Penn State vs. Iowa predictions page.

Penn State vs. Iowa prediction: Who will win, cover the spread?

Using innovative machine learning and data analysis, we have simulated the outcome of Penn State vs. Iowa 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Iowa a 59% chance of beating Penn State. Our predicted final score has Iowa winning 23-20.

According to our model, Iowa (-3) has a 53% chance of covering the spread, while the over/under total of 41.5 points has a 60% chance of staying under.

Penn State vs. Iowa odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Penn State	Iowa
Spread	+3 (-108)	-3 (-110)
Moneyline	+136	-155
Total	o41.5 (-105)	u41.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Penn State vs. Iowa picks and best bets

Our model's strongest edge in today's Penn State vs. Iowa matchup is on the spread.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Penn State vs. Iowa game-day updates and essential details

Saturday's college football matchup between Iowa and Penn State at Kinnick Stadium is scheduled to start at 7:00PM ET.

• Who: Penn State vs. Iowa
• Date: Saturday, October 18, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Kinnick Stadium

Dimers' in-depth preview of Saturday's Penn State vs. Iowa matchup includes our prediction, picks and the latest betting odds.

Before making any Penn State vs. Iowa picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Iowa, with a 59% win probability, will likely beat Penn State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Penn State vs. Iowa insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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More on college football

Stay up-to-date with the latest college football news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds offer the most up-to-date probabilities for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.