Oregon State vs. Oregon prediction: Oregon favored to win in college football Week 4, 2025

Oregon will take on Oregon State in Week 4 college football action at Autzen Stadium on Saturday, beginning at 3:00PM ET.

Based on the latest simulation results, Dimers' proven college football model predicts Oregon as the most likely winner of today's game.

For a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Oregon State vs. Oregon predictions page.

Oregon State vs. Oregon prediction: Who will win, cover the spread?

Using trusted machine learning and data analysis, we have simulated the result of Oregon State vs. Oregon 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives Oregon a 97% chance of defeating Oregon State. Our predicted final score has Oregon winning 45-12.

According to our model, the bookmakers have got it right, and Oregon State and Oregon each have a 50% chance of covering the spread, while the over/under total of 58.5 points also has an equal 50-50 chance of hitting.

Oregon State vs. Oregon odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Oregon State	Oregon
Spread	+32.5 (-115)	-32.5 (-105)
Moneyline	+3000	-10000
Total	o58.5 (-110)	u58.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Oregon State vs. Oregon picks and best bets

Our model's strongest edge in today's Oregon State vs. Oregon matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Oregon State vs. Oregon game-day updates and essential details

Saturday's college football game between Oregon and Oregon State at Autzen Stadium is scheduled to begin at 3:00PM ET.

• Who: Oregon State vs. Oregon
• Date: Saturday, September 20, 2025
• Time: 3:00PM ET/12:00PM PT
• Venue: Autzen Stadium

Dimers' full preview of Saturday's Oregon State vs. Oregon matchup includes our prediction, picks and the latest betting odds.

Before making any Oregon State vs. Oregon picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Oregon, with a 97% win probability, will likely beat Oregon State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Oregon State vs. Oregon insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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