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Ohio State vs. Michigan prediction: Why Ohio State is favored to win in college football Week 14, 2025
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Ohio State vs Michigan predictions for college football Saturday.
Michigan will face the favored Ohio State in Week 14 college football action at Michigan Stadium on Saturday, commencing at 12:00PM ET.
Based on updated simulation results, Dimers' proven college football model predicts Ohio State as the most likely winner of the Ohio State vs. Michigan game.
This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Ohio State vs. Michigan prediction: Who will win and cover?
Using powerful machine learning and data analysis, we have simulated the result of Ohio State vs. Michigan 10,000 times as part of our college football predictions coverage.
Our independent predictive model gives Ohio State a 76% chance of beating Michigan. Our predicted final score has Ohio State winning 27-18.
According to our model, the bookmakers have got it right, and Ohio State and Michigan each have a 50% chance of covering the spread, while the over/under total of 43.5 points has a 59% chance of staying under.
Ohio State vs. Michigan odds
We have sourced the best college football odds in America for this game, which are listed here:
| Bet Type | Ohio State | Michigan |
|---|---|---|
| Spread | -9.5 (-120) | +9.5 (+100) |
| Moneyline | -375 | +315 |
| Total | o43.5 (-105) | u43.5 (-110) |
All odds are correct at the time of publication and are subject to change.
Ohio State vs. Michigan picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Michigan +9.5 | +100 |
| Moneyline | Michigan | +315 |
| Total | Under 43.5 | -110 |
According to our college football best bets, the top play to make on this game is Under 43.5 total points.
Ohio State vs. Michigan game-day updates and essential details
Saturday's college football action between Michigan and Ohio State at Michigan Stadium is scheduled to begin at 12:00PM ET.
- Who: Ohio State vs. Michigan
- Date: Saturday, November 29, 2025
- Time: 12:00PM ET/9:00AM PT
- Venue: Michigan Stadium
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Conclusion
We predict Ohio State, with a 76% win probability, will likely beat Michigan on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Ohio State vs. Michigan insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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