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Northern Illinois vs. Toledo prediction: Why Toledo is favored to win in college football Week 11, 2025

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Written by Mac Douglass

Get Northern Illinois vs Toledo predictions for college football Wednesday.

Northern Illinois-Toledo Predictions and Game Preview.
Northern Illinois vs. Toledo college football gameday prediction for Wednesday, November 5, 2025.

Toledo and Northern Illinois will clash in Week 11 college football action at Glass Bowl on Wednesday, beginning at 7:00PM ET.

Based on updated simulation results, Dimers' proven college football model predicts Toledo as the most likely winner of the Northern Illinois vs. Toledo game.

This article offers a closer look at Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Northern Illinois vs. Toledo prediction: Who will win, cover the spread?

Using innovative machine learning and data, we have simulated the outcome of Northern Illinois vs. Toledo 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Toledo an 87% chance of beating Northern Illinois. Our predicted final score has Toledo winning 29-15.

According to our model, Northern Illinois (+15.5) has a 52% chance of covering the spread, while the 42.5-point over/under has a 56% chance of staying under.

 

Northern Illinois vs. Toledo odds

We have researched the best College Football odds in America for this game, which are listed here:

Bet Type Northern Illinois Toledo
Spread +15.5 (-115) -15.5 (-105)
Moneyline +500 -650
Total o42.5 (-105) u42.5 (-115)

All odds are correct at the time of publication and are subject to change.

Northern Illinois vs. Toledo picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Northern Illinois +15.5 -115
Moneyline Toledo -650
Total Under 42.5 -115

According to our college football best bets, the top play to make on this game is Under 42.5 total points.

 

Northern Illinois vs. Toledo game-day updates and essential details

Wednesday's college football action between Toledo and Northern Illinois at Glass Bowl is scheduled to commence at 7:00PM ET.

  • Who: Northern Illinois vs. Toledo
  • Date: Wednesday, November 5, 2025
  • Time: 7:00PM ET/4:00PM PT
  • Venue: Glass Bowl

Conclusion

We predict Toledo, with an 87% win probability, will likely beat Northern Illinois on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Northern Illinois vs. Toledo insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Keep up with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds provide the latest projections for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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