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North Dakota State vs. South Dakota State prediction: North Dakota State favored to win in college football Week 9, 2025

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Written by Mac Douglass

Get North Dakota State vs South Dakota State predictions for college football Saturday.

North Dakota State-South Dakota State Predictions and Game Preview.
North Dakota State vs. South Dakota State college football gameday prediction for Saturday, October 25, 2025.

South Dakota State and North Dakota State will clash in Week 9 college football action at Dana J. Dykhouse Stadium on Saturday, beginning at 8:00PM ET.

Based on updated simulations, Dimers' advanced college football model projects the North Dakota State as the most likely winner of the North Dakota State vs. South Dakota State game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

North Dakota State vs. South Dakota State prediction: Who will win, cover the spread?

Using powerful machine learning and statistical analysis, we have simulated the result of North Dakota State vs. South Dakota State 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives North Dakota State a 72% chance of beating South Dakota State. Our predicted final score has North Dakota State winning 28-20.

According to our model, North Dakota State (-6.5) has a 52% chance of covering the spread, while the over/under total of 45.5 points has a 57% chance of staying under.

 

North Dakota State vs. South Dakota State odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type North Dakota State South Dakota State
Spread -6.5 (-158) +6.5 (+124)
Moneyline -290 +260
Total o45.5 (-110) u45.5 (-110)

All odds are correct at the time of publication and are subject to change.

North Dakota State vs. South Dakota State picks and best bet

Our predictions, matched with the listed odds, reveal the top betting picks to make on this game, detailed in Dimers' college football best bets, crafted from expert modeling and analysis:

Bet Type Pick Bet Now
Spread South Dakota State +6.5 +124
Moneyline South Dakota State +260
Total Under 45.5 -110

According to our college football best bets, the top play to make on this game is Under 45.5 total points.

 

North Dakota State vs. South Dakota State game-day updates and essential details

Saturday's college football game between South Dakota State and North Dakota State at Dana J. Dykhouse Stadium is scheduled to begin at 8:00PM ET.

  • Who: North Dakota State vs. South Dakota State
  • Date: Saturday, October 25, 2025
  • Time: 8:00PM ET/5:00PM PT
  • Venue: Dana J. Dykhouse Stadium

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To make the most of Saturday's mammoth day of sports, headlined by clashes like this one for college football Saturday, check out details on the latest Bet365 bonus code "DIMERS" that secures $200 in bonus bets from a $5 bet — win or lose. Don't miss out!

Conclusion

We predict North Dakota State, with a 72% win probability, will likely beat South Dakota State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate North Dakota State vs. South Dakota State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Keep up with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds provide the latest projections for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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