Nicholls State vs. Southeastern Louisiana prediction: Southeastern Louisiana favored to win in college football Week 13, 2025

Southeastern Louisiana and Nicholls State will lock horns in Week 13 college football action at Strawberry Stadium on Thursday, beginning at 7:00PM ET.

Based on updated simulation results, Dimers' proven college football model predicts Southeastern Louisiana as the most likely winner of the Nicholls State vs. Southeastern Louisiana game.

This article offers an expanded analysis of Thursday's matchup, including an expanded look at the predicted score, best bets and picks.

Nicholls State vs. Southeastern Louisiana prediction: Who will win and cover?

Using trusted machine learning and data analysis, we have simulated the result of Nicholls State vs. Southeastern Louisiana 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives Southeastern Louisiana an 89% chance of beating Nicholls State. Our predicted final score has Southeastern Louisiana winning 32-15.

According to our model, the bookmakers have got it right, and Nicholls State and Southeastern Louisiana each have a 50% chance of covering the spread, while the over/under total of 48.5 points has a 53% chance of going over.

Nicholls State vs. Southeastern Louisiana odds

We have researched the best College Football odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Nicholls State vs. Southeastern Louisiana picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our college football best bets, the top play to make on this game is Over 48.5 total points.

Nicholls State vs. Southeastern Louisiana game-day updates and essential details

Thursday's college football matchup between Southeastern Louisiana and Nicholls State at Strawberry Stadium is scheduled to start at 7:00PM ET.

• Who: Nicholls State vs. Southeastern Louisiana
• Date: Thursday, November 20, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Strawberry Stadium

Conclusion

We predict Southeastern Louisiana, with an 89% win probability, will likely beat Nicholls State on Thursday.

AI and automation have enhanced this article to quickly deliver accurate Nicholls State vs. Southeastern Louisiana insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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