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Mets vs. Cardinals prediction: Mets favored to win Wednesday's MLB matchup [4/1/2026]
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get New York Mets vs St. Louis Cardinals predictions for MLB Wednesday.
The St. Louis Cardinals and New York Mets will meet in MLB action at Busch Stadium on Wednesday, starting at 1:15 PM ET.
Matthew Liberatore (0-0, 1.80 ERA) will start for the Cardinals, pitting him against Freddy Peralta (1-0, 7.20 ERA) for the Mets.
Based on updated simulation results, Dimers' proven MLB model predicts the Mets as the most likely winner of the Mets vs. Cardinals game.
This article offers a closer look at Wednesday's matchup, including best bets and picks.
Mets vs. Cardinals prediction: Who will win and cover?
Using innovative machine learning and data, we have simulated the outcome of Wednesday's MLB game between the Mets and Cardinals, forming part of our MLB predictions coverage.
Our independent predictive model currently gives the Mets a 59% chance of beating the Cardinals.
According to our model, the Cardinals (+1.5) have a 54% chance of covering the run line, while the 7.5-run over/under has a 53% chance of going over.
Mets vs. Cardinals odds [4/1/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Mets | Cardinals |
|---|---|---|
| Run Line | -1.5 (+126) | +1.5 (-120) |
| Moneyline | -146 | +140 |
| Total | o7.5 (+103) | u7.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Mets vs. Cardinals picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Mets -1.5 | +126 |
| Moneyline | Mets | -146 |
| Total | Over 7.5 | +103 |
According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Mets vs. Cardinals game-day updates and essential details
Wednesday's MLB action between the Cardinals and Mets at Busch Stadium is scheduled to begin at 1:15 PM ET.
- Who: New York Mets vs. St. Louis Cardinals
- Date: Wednesday, April 1, 2026
- Time: 1:15 PM ET/10:15AM PT
- Venue: Busch Stadium
Conclusion
We predict the Mets, with a 59% win probability, will likely beat the Cardinals on Wednesday.
AI and automation have enhanced this article to quickly deliver accurate Mets vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice, head to our responsible gambling hub.
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Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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