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Nebraska vs. Penn State prediction: Why Penn State is favored to win in college football Week 13, 2025

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Written by Mac Douglass

Get Nebraska vs Penn State predictions for college football Saturday.

Nebraska-Penn State Predictions and Game Preview.
Nebraska vs. Penn State college football gameday prediction for Saturday, November 22, 2025.

Penn State and Nebraska will clash in Week 13 college football action at West Shore Home Field at Beaver Stadium on Saturday, commencing at 7:00PM ET.

Based on the latest simulation results, Dimers' proven college football model projects Penn State as the most likely winner of the Nebraska vs. Penn State game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Nebraska vs. Penn State prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Nebraska vs. Penn State 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Penn State a 67% chance of defeating Nebraska. Our predicted final score has Penn State winning 25-20.

According to our model, Nebraska (+7) has a 55% chance of covering the spread, while the over/under total of 45.5 points has a 53% chance of staying under.

 

Nebraska vs. Penn State odds

We have sourced the best College Football odds in America for this game, which are listed here:

Bet Type Nebraska Penn State
Spread +7 (-105) -7 (-115)
Moneyline +230 -275
Total o45.5 (-104) u45.5 (-110)

All odds are correct at the time of publication and are subject to change.

Nebraska vs. Penn State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Nebraska +7 -105
Moneyline Nebraska +230
Total Under 45.5 -110

According to our best college football bets, the top play to make on this game is Nebraska +7 at the spread.

 

Nebraska vs. Penn State game-day updates and essential details

Saturday's college football game between Penn State and Nebraska at West Shore Home Field at Beaver Stadium is scheduled to begin at 7:00PM ET.

  • Who: Nebraska vs. Penn State
  • Date: Saturday, November 22, 2025
  • Time: 7:00PM ET/4:00PM PT
  • Venue: West Shore Home Field at Beaver Stadium

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Conclusion

We predict Penn State, with a 67% win probability, will likely beat Nebraska on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Nebraska vs. Penn State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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