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Free MLB picks today: Thursday's MLB best bets include two over/under plays [10/16/2025]

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Written by Dave Garofolo

Get free MLB picks today and best bets for Thursday, October 16, 2025.

MLB Best Bets.
These MLB betting picks for October 16, 2025, are based on the latest odds and probabilities for Thursday's games.

Today’s free MLB picks for October 16, 2025 are here, with Thursday’s MLB best bets built on thousands of predictive simulations analyzing the latest odds and matchups.

These MLB best bets include matchups like Blue Jays vs. Mariners and Brewers vs. Dodgers, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

But if you're serious about long-term profit, it's not just about probability—it's about edge. To unlock our highest-edge MLB bets—the ones with true long-term value—join Dimers Pro.

Pro members get unlimited access to everything Dimers has to offer on Thursday, October 16, 2025, including our full set of picks and best bets for today and the week ahead.

List of MLB best bets today [10/16, updated 6:02PM ET]

After crunching the numbers and conducting thousands of simulations, our independent predictive analytics model has identified the best baseball bets for Thursday, October 16, 2025.

Blue Jays vs. Mariners over 7.5 runs (-108)

Our model has pinpointed a high-probability MLB betting opportunity today, which comes in the Blue Jays vs. Mariners game. We recommend an over/under bet on over 7.5 runs at -108 odds, with our analysis showing a 64.7% chance of hitting and a compelling edge of 12.8%.

 

Brewers vs. Dodgers over 8 runs(-102)

Our model has found another strong MLB playoffs bet for Thursday's baseball action, this time in the matchup between the Brewers and Dodgers. We suggest placing an over/under wager on over 8 runs at -102 odds, with a 58.6% probability delivering an 8.1% edge.

 

MLB Playoffs best bets: Thursday, 10/16/2025

As of 6:02PM ET, here are our top two MLB bets by probability recommended by our model:

Matchup Bet Odds Probability Edge
Blue Jays vs. Mariners Over 7.5 Runs -108 @ FanDuel 64.7% 12.8%
Brewers vs. Dodgers Over 8 Runs -102 @ BetMGM 58.6% 8.1%

Dimers Pro unlocks instant access to the most valuable bets across all sports, powered by our advanced predictive model.

Today, Dimers Pro subscribers have access to two MLB picks—with access to all of these being what makes a difference over time.

Join Dimers Pro now to access these picks, as well as a comprehensive range of props, trends and parlays for October 16, 2025.

List of upcoming MLB postseason games to bet on [10/16/2025]

Bet365 bonus code "DIMERS" — perfect for MLB Thursday betting

To make the most of Thursday's MLB best bets, including the Blue Jays vs. Mariners matchup, check out the new Bet365 bonus code "DIMERS" that unlocks $200 in bonus bets from a $5 bet – win or lose. Don't miss out!

More on MLB

The bets on this page form part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

Our MLB best bets are locked and loaded for October 16, 2025, featuring plays such as over 7.5 runs in the Blue Jays vs. Mariners matchup and over 8 runs in the Brewers vs. Dodgers matchup. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

Note: Clicking links to our sportsbook partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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