Missouri vs. Vanderbilt prediction: Vanderbilt favored to win in college football Week 9, 2025

Vanderbilt will square off with Missouri in Week 9 college football action at FirstBank Stadium on Saturday, with kickoff at 3:30PM ET.

Based on the latest simulations, Dimers' advanced college football model predicts the Vanderbilt as the most likely winner of the Missouri vs. Vanderbilt game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Missouri vs. Vanderbilt prediction: Who will win, cover the spread?

Using innovative machine learning and data, we have simulated the outcome of Missouri vs. Vanderbilt 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives Vanderbilt a 62% chance of defeating Missouri. Our predicted final score has Vanderbilt winning 27-23.

According to our model, Vanderbilt (-3) has a 56% chance of covering the spread, while the 52.5-point over/under has a 53% chance of going over.

Missouri vs. Vanderbilt odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Missouri	Vanderbilt
Spread	+3 (-105)	-3 (-115)
Moneyline	+132	-155
Total	o52.5 (-104)	u52.5 (-110)

All odds are correct at the time of publication and are subject to change.

Missouri vs. Vanderbilt picks and best bet

Our predictions, matched with the current odds, reveal the top betting picks for this game, detailed in Dimers' best college football bets, crafted from expert modeling and analysis:

Bet Type	Pick	Bet Now
Spread	Vanderbilt -3	-115
Moneyline	Vanderbilt	-155
Total	Over 52.5	-104

According to our college football best bets, the top play to make on this game is Vanderbilt -3 at the spread.

Missouri vs. Vanderbilt game-day updates and essential details

Saturday's college football matchup between Vanderbilt and Missouri at FirstBank Stadium is scheduled to start at 3:30PM ET.

• Who: Missouri vs. Vanderbilt
• Date: Saturday, October 25, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: FirstBank Stadium

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Conclusion

We predict Vanderbilt, with a 62% win probability, will likely beat Missouri on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Missouri vs. Vanderbilt insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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