Mississippi State vs. Arkansas prediction: Why Arkansas is favored to win in college football Week 10, 2025

Arkansas and Mississippi State will meet in Week 10 college football action at Donald W. Reynolds Razorback Stadium on Saturday, beginning at 4:00PM ET.

Based on updated simulations, Dimers' advanced college football model projects the Arkansas as the most likely winner of the Mississippi State vs. Arkansas game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Mississippi State vs. Arkansas prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the result of Mississippi State vs. Arkansas 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives Arkansas a 55% chance of defeating Mississippi State. Our predicted final score has Arkansas winning 32-30.

According to our model, Mississippi State (+4.5) has a 59% chance of covering the spread, while the over/under total of 66.5 points has a 56% chance of going over.

Mississippi State vs. Arkansas odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Mississippi State	Arkansas
Spread	+4.5 (-105)	-4.5 (-115)
Moneyline	+170	-198
Total	o66.5 (-110)	u66.5 (-105)

All odds are correct at the time of publication and are subject to change.

Mississippi State vs. Arkansas picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Mississippi State +4.5	-105
Moneyline	Mississippi State	+170
Total	Over 66.5	-110

According to our college football best bets, the top play to make on this game is Mississippi State +4.5 at the spread.

Mississippi State vs. Arkansas game-day updates and essential details

Saturday's college football matchup between Arkansas and Mississippi State at Donald W. Reynolds Razorback Stadium is scheduled to commence at 4:00PM ET.

• Who: Mississippi State vs. Arkansas
• Date: Saturday, November 1, 2025
• Time: 4:00PM ET/1:00PM PT
• Venue: Donald W. Reynolds Razorback Stadium

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Conclusion

We predict Arkansas, with a 55% win probability, will likely beat Mississippi State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Mississippi State vs. Arkansas insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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