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Minnesota vs. Northwestern prediction: Northwestern favored to win in college football Week 13, 2025

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Written by Mac Douglass

Get Minnesota vs Northwestern predictions for college football Saturday.

Minnesota-Northwestern Predictions and Game Preview.
Minnesota vs. Northwestern college football gameday prediction for Saturday, November 22, 2025.

Northwestern will take on Minnesota in Week 13 college football action at Wrigley Field on Saturday, starting at 12:00PM ET.

Based on the latest simulation results, Dimers' proven college football model gives Northwestern a slight edge with a 51% win probability over Minnesota.

This article offers a closer look at Saturday's Minnesota vs. Northwestern matchup, including an expanded look at the predicted score, best bets and picks.

Minnesota vs. Northwestern prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the result of Minnesota vs. Northwestern 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives Northwestern a 51% chance of defeating Minnesota. Our predicted score is Minnesota 22-22 Northwestern.

According to our model, Minnesota (+3.5) has a 61% chance of covering the spread, while the over/under total of 41.5 points has a 56% chance of staying under.

While there is no way for a College Football game to end in a tie, our prediction of 22-22 is based on each team's average score in the above-mentioned simulations of Minnesota vs. Northwestern.

 

Minnesota vs. Northwestern odds

We have sourced the best College Football odds in America for this game, which are listed here:

Bet Type Minnesota Northwestern
Spread +3.5 (-105) -3.5 (-115)
Moneyline +160 -176
Total o41.5 (-106) u41.5 (-110)

All odds are correct at the time of publication and are subject to change.

Minnesota vs. Northwestern picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Minnesota +3.5 -105
Moneyline Minnesota +160
Total Under 41.5 -110

According to our best college football bets, the top play to make on this game is Minnesota to win.

 

Minnesota vs. Northwestern game-day updates and essential details

Saturday's college football action between Northwestern and Minnesota at Wrigley Field is scheduled to start at 12:00PM ET.

  • Who: Minnesota vs. Northwestern
  • Date: Saturday, November 22, 2025
  • Time: 12:00PM ET/9:00AM PT
  • Venue: Wrigley Field

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To make the most of the upcoming Missouri launch, check out details on the latest Bet365 bonus code "DIMERS" that unlocks $365 in bonus bets from a $10 bet — win or lose. Don't miss out!

Conclusion

We predict Northwestern, with a 51% win probability, will likely beat Minnesota on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Minnesota vs. Northwestern insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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