Twins vs. White Sox prediction: Why White Sox are favored to win Thursday's MLB matchup [5/28/2026]

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Written by Jason Bevilacqua

Get Minnesota Twins vs Chicago White Sox predictions for MLB Thursday.

Minnesota Twins-Chicago White Sox Predictions and Game Preview.
Minnesota Twins vs. Chicago White Sox MLB prediction for Thursday, May 28, 2026.

The Chicago White Sox and Minnesota Twins will lock horns in MLB action at Rate Field on Thursday, starting at 2:10 PM ET.

The White Sox will start Davis Martin (7-1, 2.04 ERA), up against Kendry Rojas (1-0, 1.26 ERA) for the Twins.

Based on updated simulation results, Dimers' proven MLB model predicts the White Sox as the most likely winner of the Twins vs. White Sox game.

This article offers an expanded analysis of Thursday's matchup, including best bets and picks.

Twins vs. White Sox prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the result of Thursday's MLB game between the Twins and White Sox, forming part of our MLB predictions coverage.

Our leading predictive model gives the White Sox a 56% chance of defeating the Twins.

According to our model, the Twins (+1.5) have a 62% chance of covering the run line, while the 7.5-run over/under has a 56% chance of going over.

 

Twins vs. White Sox odds [5/28/2026]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type Twins White Sox
Run Line +1.5 (-166) -1.5 (+141)
Moneyline +136 -157
Total o7.5 (-111) u7.5 (-105)

All odds are correct at the time of publication and are subject to change.

Twins vs. White Sox picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Run Line Twins +1.5 -166
Moneyline Twins +136
Total Over 7.5 -111

According to our MLB best bets, the top play to make on this game is Over 7.5 total runs.

These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.

 

Twins vs. White Sox game-day updates and essential details

Thursday's MLB matchup between the White Sox and Twins at Rate Field is scheduled to begin at 2:10 PM ET.

Conclusion

We predict the White Sox, with a 56% win probability, will likely beat the Twins in Thursday's MLB matchup.

Additional tools and information for betting safely can be found in our Responsible Gambling hub.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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