Brewers vs. Red Sox prediction: Boston favored to win Wednesday's MLB matchup [4/8/2026]

The Boston Red Sox will face the Milwaukee Brewers in MLB action at Fenway Park on Wednesday, commencing at 1:35 PM ET.

Sonny Gray (1-0, 4.50 ERA) will start on the mound for the Red Sox, while the Brewers have opted for Shane Drohan (0-0, 0.00 ERA).

Based on the latest simulation results, Dimers' proven MLB model predicts the Red Sox as the most likely winner of the Brewers vs. Red Sox game.

This article offers a closer look at Wednesday's matchup, including best bets and picks.

Brewers vs. Red Sox prediction: Who will win and cover?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB matchup between the Brewers and Red Sox, forming part of our MLB predictions coverage.

Our independent predictive model gives the Red Sox a 55% chance of defeating the Brewers.

According to our model, the Brewers (+1.5) have a 63% chance of covering the run line, while the 7-run over/under has a 57% chance of going over.

Brewers vs. Red Sox odds [4/8/2026]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Brewers vs. Red Sox picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: