Michigan vs. Michigan State prediction: Why Michigan is favored to win in college football Week 9, 2025

Michigan State and Michigan will lock horns in Week 9 college football action at Spartan Stadium on Saturday, with kickoff at 7:30PM ET.

Based on the latest simulation results, Dimers' proven college football model predicts the Michigan as the most likely winner of the Michigan vs. Michigan State game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Michigan vs. Michigan State prediction: Who will win, cover the spread?

Using powerful machine learning and data analysis, we have simulated the result of Michigan vs. Michigan State 10,000 times as part of our college football predictions coverage.

Our famous predictive model gives Michigan an 85% chance of defeating Michigan State. Our predicted final score has Michigan winning 29-16.

According to our model, Michigan State (+14) has a 52% chance of covering the spread, while the 47.5-point over/under has a 54% chance of going over.

Michigan vs. Michigan State odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Michigan	Michigan State
Spread	-14 (-110)	+14 (-110)
Moneyline	-520	+430
Total	o47.5 (-110)	u47.5 (-105)

All odds are correct at the time of publication and are subject to change.

Michigan vs. Michigan State picks and best bet

Our predictions, matched with the best odds, reveal the top betting picks to place on this game, detailed in Dimers' college football best bets, crafted from expert modeling and analysis:

Bet Type	Pick	Bet Now
Spread	Michigan State +14	-110
Moneyline	Michigan	-520
Total	Over 47.5	-110

According to our best college football bets, the top play to make on this game is Over 47.5 total points.

Michigan vs. Michigan State game-day updates and essential details

Saturday's college football matchup between Michigan State and Michigan at Spartan Stadium is scheduled to commence at 7:30PM ET.

• Who: Michigan vs. Michigan State
• Date: Saturday, October 25, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Spartan Stadium

Sports betting deal available for NCAAF Saturday

To make the most of Saturday's enormous day of sports, headlined by clashes like this one for college football Saturday, check out details on the latest Bet365 bonus code "DIMERS" that unlocks $200 in bonus bets from a $5 bet — win or lose. Don't miss out!

Conclusion

We predict Michigan, with an 85% win probability, will likely beat Michigan State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Michigan vs. Michigan State insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Stay up-to-date with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds offer the latest projections for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.