Miami (FL) vs. Ohio State prediction: Ohio State favored to win Cotton Bowl Classic [2025]

Ohio State and Miami Florida will lock horns in the 2025 Cotton Bowl Classic at AT&T Stadium on Wednesday, with kickoff at 7:30 PM ET.

Based on updated simulations, Dimers' proven college football model predicts Ohio State as the most likely winner of the Miami (FL) vs. Ohio State game.

This article offers further insights into Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Cotton Bowl Classic prediction: Who will win and cover?

Using powerful machine learning and data, we have simulated the outcome of the 2025 Cotton Bowl Classic 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives Ohio State a 73% chance of defeating Miami Florida. Our predicted final score has Ohio State winning 24-16.

According to our model, Miami Florida (+9.5) has a 52% chance of covering the spread, while the 41.5-point over/under has a 53% chance of staying under.

Cotton Bowl Classic odds

We have researched the best college football odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Miami (FL) vs. Ohio State picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: