UMass vs. Iowa prediction: Why Iowa is favored to win in college football Week 3, 2025

Iowa will square off with Massachusetts in Week 3 college football action at Kinnick Stadium on Saturday, beginning at 7:30PM ET.

Based on updated simulation results, Dimers' proven college football model predicts Iowa as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive UMass vs. Iowa predictions page.

UMass vs. Iowa prediction: Who will win, cover the spread?

Using trusted machine learning and data, we have simulated the result of UMass vs. Iowa 10,000 times as part of our college football predictions coverage.

Our leading predictive model currently gives Iowa a 100% chance of defeating Massachusetts. Our predicted final score has Iowa winning 40-5.

According to our model, the bookies have got it right, and Massachusetts and Iowa each have a 50% chance of covering the spread, while the over/under total of 44.5 points has a 55% chance of staying under.

UMass vs. Iowa odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	UMass	Iowa
Spread	+35.5 (-118)	-35.5 (-102)
Moneyline	+8000	-100000
Total	o44.5 (-110)	u44.5 (-105)

All odds are correct at the time of publication and are subject to change.

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UMass vs. Iowa picks and best bets

Our model's strongest edge in today's UMass vs. Iowa matchup is on the spread.

Our expert predictions, aligned with the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

UMass vs. Iowa game-day updates and essential details

Saturday's college football game between Iowa and UMass at Kinnick Stadium is scheduled to begin at 7:30PM ET.

• Who: Massachusetts vs. Iowa
• Date: Saturday, September 13, 2025
• Time: 7:30PM ET/4:30PM PT
• Venue: Kinnick Stadium

Dimers' full preview of Saturday's UMass vs. Iowa matchup includes our prediction, picks and the latest betting odds.

Before making any UMass vs. Iowa picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Iowa, with a 100% win probability, will likely beat Massachusetts on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Massachusetts vs. Iowa insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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