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Louisville vs. Miami (FL) prediction: Why Miami Florida is favored to win in college football Week 8, 2025

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Written by Mac Douglass

Get Louisville vs Miami (FL) predictions for college football Friday.

Louisville-Miami (FL) Predictions and Game Preview.
Louisville vs. Miami (FL) college football gameday prediction for Friday, October 17, 2025.

Miami Florida will square off with Louisville in Week 8 college football action at Hard Rock Stadium on Friday, beginning at 7:00PM ET.

Based on the latest simulations, Dimers' advanced college football model projects the Miami Florida as the most likely winner of today's game.

For a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Louisville vs. Miami (FL) predictions page.

Louisville vs. Miami (FL) prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the outcome of Louisville vs. Miami (FL) 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Miami Florida a 69% chance of beating Louisville. Our predicted final score has Miami Florida winning 28-21.

According to our model, Louisville (+11.5) has a 59% chance of covering the spread, while the 49.5-point over/under has an equal 50-50 chance of hitting.

 

Louisville vs. Miami (FL) odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type Louisville Miami (FL)
Spread +11.5 (-115) -11.5 (-105)
Moneyline +340 -430
Total o49.5 (-105) u49.5 (-110)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Louisville vs. Miami (FL) picks and best bets

Our model's strongest edge in today's Louisville vs. Miami (FL) matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Louisville vs. Miami (FL) game-day updates and essential details

Friday's college football matchup between Miami (FL) and Louisville at Hard Rock Stadium is scheduled to commence at 7:00PM ET.

  • Who: Louisville vs. Miami Florida
  • Date: Friday, October 17, 2025
  • Time: 7:00PM ET/4:00PM PT
  • Venue: Hard Rock Stadium

Dimers' comprehensive preview of Friday's Louisville vs. Miami (FL) matchup includes our prediction, picks and the latest betting odds.

Before making any Louisville vs. Miami (FL) picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

Conclusion

We predict Miami Florida, with a 69% win probability, will likely beat Louisville on Friday.

AI and automation have enhanced this article to quickly deliver accurate Louisville vs. Miami Florida insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Stay up-to-date with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds provide the most accurate projections for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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