Louisiana-Monroe vs. Louisiana-Lafayette prediction: Louisiana-Lafayette favored to win in college football Week 14, 2025

Louisiana-Lafayette and Louisiana-Monroe will meet in Week 14 college football action at Cajun Field at Our Lady of Lourdes Stadium on Saturday, commencing at 3:00PM ET.

Based on the latest simulation results, Dimers' advanced college football model predicts Louisiana-Lafayette as the most likely winner of the Louisiana-Monroe vs. Louisiana-Lafayette game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Louisiana-Monroe vs. Louisiana-Lafayette prediction: Who will win and cover?

Using innovative machine learning and data, we have simulated the outcome of Louisiana-Monroe vs. Louisiana-Lafayette 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Louisiana-Lafayette a 70% chance of beating Louisiana-Monroe. Our predicted final score has Louisiana-Lafayette winning 28-21.

According to our model, Louisiana-Monroe (+11.5) has a 58% chance of covering the spread, while the 47.5-point over/under has a 55% chance of staying under.

Louisiana-Monroe vs. Louisiana-Lafayette odds

We have sourced the best college football odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Louisiana-Monroe vs. Louisiana-Lafayette picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our college football best bets, the top play to make on this game is Louisiana-Monroe to win.

Louisiana-Monroe vs. Louisiana-Lafayette game-day updates and essential details

Saturday's college football action between Louisiana-Lafayette and Louisiana-Monroe at Cajun Field at Our Lady of Lourdes Stadium is scheduled to commence at 3:00PM ET.

• Who: Louisiana-Monroe vs. Louisiana-Lafayette
• Date: Saturday, November 29, 2025
• Time: 3:00PM ET/12:00PM PT
• Venue: Cajun Field at Our Lady of Lourdes Stadium

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Conclusion

We predict Louisiana-Lafayette, with a 70% win probability, will likely beat Louisiana-Monroe on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Louisiana-Monroe vs. Louisiana-Lafayette insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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