Lorenzo Musetti vs. Novak Djokovic prediction, odds, picks for 2026 Australian Open

Lorenzo Musetti and Novak Djokovic will meet in the quarterfinals of the 2026 Australian Open on Tuesday.

Based on updated simulation results, Dimers' proven tennis model predicts Novak Djokovic as the most likely winner of the Musetti vs. Djokovic match.

This article offers a closer look at Tuesday's match, including best bets and picks.

Musetti vs. Djokovic prediction: Who will win and advance to the semifinals?

Using innovative machine learning and statistical analysis, we have simulated the outcome of Tuesday's Musetti-Djokovic men's singles match 10,000 times as part of our tennis predictions coverage.

Our leading predictive model gives Djokovic a 76% chance of winning against Musetti in the 2026 Australian Open.

Additionally, Djokovic has a 69% chance of winning the first set. The simulations also show Djokovic (-4.5) has a 53% chance of covering the games spread, while the under 38.5 games has a 59% chance of hitting**, according to our model.

Lorenzo Musetti vs. Novak Djokovic odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

All odds are correct at the time of publication and are subject to change.

Musetti vs. Djokovic picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: