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Kentucky vs. Vanderbilt prediction: Vanderbilt favored to win in college football Week 13, 2025
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Kentucky vs Vanderbilt predictions for college football Saturday.
Vanderbilt will take on Kentucky in Week 13 college football action at FirstBank Stadium on Saturday, starting at 3:30PM ET.
Based on updated simulation results, Dimers' advanced college football model predicts Vanderbilt as the most likely winner of the Kentucky vs. Vanderbilt game.
This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Kentucky vs. Vanderbilt prediction: Who will win and cover?
Using powerful machine learning and data, we have simulated the outcome of Kentucky vs. Vanderbilt 10,000 times as part of our college football predictions coverage.
Our famous predictive model gives Vanderbilt a 65% chance of defeating Kentucky. Our predicted final score has Vanderbilt winning 30-24.
According to our model, Kentucky (+7.5) has a 55% chance of covering the spread, while the 53.5-point over/under has a 52% chance of staying under.
Kentucky vs. Vanderbilt odds
We have researched the best College Football odds in America for this game, which are listed here:
| Bet Type | Kentucky | Vanderbilt |
|---|---|---|
| Spread | +7.5 (-115) | -7.5 (+100) |
| Moneyline | +240 | -270 |
| Total | o53.5 (-112) | u53.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Kentucky vs. Vanderbilt picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Kentucky +7.5 | -115 |
| Moneyline | Kentucky | +240 |
| Total | Under 53.5 | -105 |
According to our college football best bets, the top play to make on this game is Kentucky to win.
Kentucky vs. Vanderbilt game-day updates and essential details
Saturday's college football action between Vanderbilt and Kentucky at FirstBank Stadium is scheduled to start at 3:30PM ET.
- Who: Kentucky vs. Vanderbilt
- Date: Saturday, November 22, 2025
- Time: 3:30PM ET/12:30PM PT
- Venue: FirstBank Stadium
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Conclusion
We predict Vanderbilt, with a 65% win probability, will likely beat Kentucky on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Kentucky vs. Vanderbilt insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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