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Katerina Siniakova vs. Amanda Anisimova prediction, odds, picks for Australian Open 2026
Updated: | First published:
Written by Ryan Leaver, Senior Sports and Betting Editor
Get Siniakova vs Anisimova predictions for Australian Open 2026.
Katerina Siniakova and Amanda Anisimova are scheduled to meet in the second round of the Australian Open 2026 on Wednesday.
Based on the latest simulation results, Dimers' proven tennis model projects Amanda Anisimova as the most likely winner of the Siniakova vs. Anisimova match.
This article offers a closer look at Wednesday's match, including best bets and picks.
Siniakova vs. Anisimova prediction: Who will win and advance to the round of 32?
Using innovative machine learning and data analysis, we have simulated the result of Wednesday's Siniakova-Anisimova women's singles match 10,000 times as part of our tennis predictions coverage.
Our leading predictive model gives Anisimova a 76% chance of defeating Siniakova in the Australian Open 2026.
Additionally, Anisimova has a 71% chance of winning the first set. The simulations also show Anisimova (-4.5) has a 53% chance of covering the games spread, while the under 21.5 games has a 56% chance of hitting**, according to our model.
Katerina Siniakova vs. Amanda Anisimova odds
We have sourced the most up-to-date betting odds in America for this match, which are listed here:
| Bet Type | Siniakova | Anisimova |
|---|---|---|
| Moneyline | +275 | -325 |
| First Set | +200 | -250 |
| Game Spread | +4.5 (-110) | -4.5 (-122) |
| Total Games | o21.5 (-105) | u21.5 (-140) |
All odds are correct at the time of publication and are subject to change.
Siniakova vs. Anisimova picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Anisimova | -325 |
| First Set | Anisimova | -140 |
According to our tennis best bets, the top play to make on this match is over 21.5 total games.
Siniakova vs. Anisimova updates and essential details
The Australian Open 2026 match between Katerina Siniakova and Amanda Anisimova is scheduled to commence on Wednesday at 10:50 PM ET.
- Who: Katerina Siniakova vs. Amanda Anisimova
- Date: Wednesday, January 21, 2026
- Approx. Time: 10:50 PM ET/7:50PM PT
- Tournament: Australian Open Women's Singles 2026
- Round: Second round
All dates and times in this article are United States Eastern Time unless otherwise noted.
Conclusion
We predict Amanda Anisimova, with a 76% win probability, will likely beat Katerina Siniakova at the Australian Open 2026.
AI and automation have enhanced this article to quickly deliver accurate Siniakova vs. Anisimova insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.
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