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Jacksonville State vs. Middle Tennessee prediction: Why Jacksonville State is favored to win in college football Week 10, 2025

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Written by Mac Douglass

Get Jacksonville State vs Middle Tennessee predictions for college football Wednesday.

Jacksonville State-Middle Tennessee Predictions and Game Preview.
Jacksonville State vs. Middle Tennessee college football gameday prediction for Wednesday, October 29, 2025.

Middle Tennessee will take on Jacksonville State in Week 10 college football action at Johnny "Red" Floyd Stadium on Wednesday, commencing at 7:30PM ET.

Based on updated simulations, Dimers' proven college football model predicts the Jacksonville State as the most likely winner of the Jacksonville State vs. Middle Tennessee game.

This article offers an expanded analysis of Wednesday's matchup, including an expanded look at the predicted score, best bets and picks.

Jacksonville State vs. Middle Tennessee prediction: Who will win, cover the spread?

Using innovative machine learning and data analysis, we have simulated the outcome of Jacksonville State vs. Middle Tennessee 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Jacksonville State a 51% chance of beating Middle Tennessee. Our predicted final score has Jacksonville State winning 28-27.

According to our model, Middle Tennessee (+4) has a 64% chance of covering the spread, while the over/under total of 53.5 points has a 51% chance of staying under.

 

Jacksonville State vs. Middle Tennessee odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type Jacksonville State Middle Tennessee
Spread -4 (-112) +4 (-108)
Moneyline -190 +164
Total o53.5 (-110) u53.5 (-105)

All odds are correct at the time of publication and are subject to change.

Jacksonville State vs. Middle Tennessee picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Middle Tennessee +4 -108
Moneyline Middle Tennessee +164
Total Under 53.5 -105

According to our college football best bets, the top play to make on this game is Middle Tennessee +4 at the spread.

 

Jacksonville State vs. Middle Tennessee game-day updates and essential details

Wednesday's college football matchup between Middle Tennessee and Jacksonville State at Johnny "Red" Floyd Stadium is scheduled to begin at 7:30PM ET.

  • Who: Jacksonville State vs. Middle Tennessee
  • Date: Wednesday, October 29, 2025
  • Time: 7:30PM ET/4:30PM PT
  • Venue: Johnny "Red" Floyd Stadium

Conclusion

We predict Jacksonville State, with a 51% win probability, will likely beat Middle Tennessee on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Jacksonville State vs. Middle Tennessee insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on college football

Keep up with the latest college football betting news and CFB parlay picks throughout the season. Plus, our College Football National Championship odds provide the most accurate predictions for the national title game and major conferences.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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