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Iowa State vs. Oklahoma State prediction: Iowa State favored to win in college football Week 14, 2025
Updated: | First published:
Written by Mac Douglass, Senior Editor
Get Iowa State vs Oklahoma State predictions for college football Saturday.
Oklahoma State will take on the favored Iowa State in Week 14 college football action at Boone Pickens Stadium on Saturday, starting at 12:00PM ET.
Based on updated simulation results, Dimers' proven college football model predicts Iowa State as the most likely winner of the Iowa State vs. Oklahoma State game.
This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.
Iowa State vs. Oklahoma State prediction: Who will win and cover?
Using powerful machine learning and data analysis, we have simulated the result of Iowa State vs. Oklahoma State 10,000 times as part of our college football predictions coverage.
Our famous predictive model gives Iowa State an 84% chance of beating Oklahoma State. Our predicted final score has Iowa State winning 30-16.
According to our model, Oklahoma State (+14) has a 52% chance of covering the spread, while the 46.5-point over/under has a 52% chance of staying under.
Iowa State vs. Oklahoma State odds
We have researched the best college football odds in America for this game, which are listed here:
| Bet Type | Iowa State | Oklahoma State |
|---|---|---|
| Spread | -14 (-110) | +14 (-108) |
| Moneyline | -625 | +520 |
| Total | o46.5 (-110) | u46.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Iowa State vs. Oklahoma State picks and best bet
After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Spread | Oklahoma State +14 | -108 |
| Moneyline | Oklahoma State | +520 |
| Total | Under 46.5 | -105 |
According to our college football best bets, the top play to make on this game is Under 46.5 total points.
Iowa State vs. Oklahoma State game-day updates and essential details
Saturday's college football action between Oklahoma State and Iowa State at Boone Pickens Stadium is scheduled to begin at 12:00PM ET.
- Who: Iowa State vs. Oklahoma State
- Date: Saturday, November 29, 2025
- Time: 12:00PM ET/9:00AM PT
- Venue: Boone Pickens Stadium
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Conclusion
We predict Iowa State, with an 84% win probability, will likely beat Oklahoma State on Saturday.
AI and automation have enhanced this article to quickly deliver accurate Iowa State vs. Oklahoma State insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
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Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.
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