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Illinois vs. Wisconsin prediction: Why Illinois is favored to win in college football Week 13, 2025

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Written by Mac Douglass

Get Illinois vs Wisconsin predictions for college football Saturday.

Illinois-Wisconsin Predictions and Game Preview.
Illinois vs. Wisconsin college football gameday prediction for Saturday, November 22, 2025.

Wisconsin and Illinois will lock horns in Week 13 college football action at Camp Randall Stadium on Saturday, beginning at 7:30PM ET.

Based on the latest simulations, Dimers' proven college football model predicts Illinois as the most likely winner of the Illinois vs. Wisconsin game.

This article offers further insights into Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Illinois vs. Wisconsin prediction: Who will win and cover?

Using innovative machine learning and data analysis, we have simulated the outcome of Illinois vs. Wisconsin 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives Illinois a 74% chance of beating Wisconsin. Our predicted final score has Illinois winning 26-18.

According to our model, the bookies have got it right, and Illinois and Wisconsin each have a 50% chance of covering the spread, while the over/under total of 42.5 points has a 60% chance of staying under.

 

Illinois vs. Wisconsin odds

We have researched the best College Football odds in America for this game, which are listed here:

Bet Type Illinois Wisconsin
Spread -8.5 (-105) +8.5 (-105)
Moneyline -298 +275
Total o42.5 (-110) u42.5 (-110)

All odds are correct at the time of publication and are subject to change.

Illinois vs. Wisconsin picks and best bet

After matching our probabilities against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Illinois -8.5 -105
Moneyline Wisconsin +275
Total Under 42.5 -110

According to our college football best bets, the top play to make on this game is Under 42.5 total points.

 

Illinois vs. Wisconsin game-day updates and essential details

Saturday's college football matchup between Wisconsin and Illinois at Camp Randall Stadium is scheduled to begin at 7:30PM ET.

  • Who: Illinois vs. Wisconsin
  • Date: Saturday, November 22, 2025
  • Time: 7:30PM ET/4:30PM PT
  • Venue: Camp Randall Stadium

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Conclusion

We predict Illinois, with a 74% win probability, will likely beat Wisconsin on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Illinois vs. Wisconsin insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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