Illinois State vs. Villanova prediction: Illinois State favored to win in college football Week 17 [2025]

Villanova and Illinois State will lock horns in Week 17 college football action at Villanova Stadium on Saturday, starting at 7:30 PM ET.

Based on the latest simulations, Dimers' proven college football model gives Illinois State a slight edge with a 54% win probability over Villanova.

This article offers an expanded analysis of Saturday's Illinois State vs. Villanova matchup, including an expanded look at the predicted score, best bets and picks.

Illinois State vs. Villanova prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Illinois State vs. Villanova 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Illinois State a 54% chance of beating Villanova. Our predicted final score has Illinois State winning 25-24.

According to our model, Villanova (+2.5) has a 52% chance of covering the spread, while the over/under total of 51.5 points has a 56% chance of going over.

Illinois State vs. Villanova odds

We have researched the best college football odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Illinois State vs. Villanova picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: