Illinois State vs. Indiana State prediction: Why Illinois State is favored to win in college football Week 11, 2025

Indiana State will square off with the favored Illinois State in Week 11 college football action at Memorial Stadium on Saturday, beginning at 1:00PM ET.

Based on updated simulation results, Dimers' proven college football model projects Illinois State as the most likely winner of the Illinois State vs. Indiana State game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Illinois State vs. Indiana State prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the outcome of Illinois State vs. Indiana State 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Illinois State a 74% chance of beating Indiana State. Our predicted final score has Illinois State winning 33-23.

According to our model, the bookmakers have got it right, and Illinois State and Indiana State each have a 50% chance of covering the spread, while the 58.5-point over/under has a 54% chance of going over.

Illinois State vs. Indiana State odds

We have researched the best College Football odds in America for this game, which are listed here:

Bet Type	Illinois State	Indiana State
Spread	-10.5 (-110)	+10.5 (-110)
Moneyline	-440	+350
Total	o58.5 (-110)	u58.5 (-108)

All odds are correct at the time of publication and are subject to change.

Illinois State vs. Indiana State picks and best bet

After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type	Pick	Bet Now
Spread	Illinois State -10.5	-110
Moneyline	Indiana State	+350
Total	Over 58.5	-110

According to our best college football bets, the top play to make on this game is Indiana State to win.

Illinois State vs. Indiana State game-day updates and essential details

Saturday's college football matchup between Indiana State and Illinois State at Memorial Stadium is scheduled to commence at 1:00PM ET.

• Who: Illinois State vs. Indiana State
• Date: Saturday, November 8, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Memorial Stadium

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Conclusion

We predict Illinois State, with a 74% win probability, will likely beat Indiana State on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Illinois State vs. Indiana State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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