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Astros vs. Mariners prediction: Seattle favored to win Monday's MLB matchup [4/13/2026]
Updated: | First published:
Written by Jason Bevilacqua, Head of Content and Communities
Get Houston Astros vs Seattle Mariners predictions for MLB Monday.
The Seattle Mariners will square off with the Houston Astros in MLB action at T-Mobile Park on Monday, commencing at 4:10 PM ET.
George Kirby (1-2, 3.60 ERA) will start on the mound for the Mariners, while the Astros are going with Mike Burrows (1-2, 5.62 ERA).
Based on updated simulations, Dimers' proven MLB model predicts the Mariners as the most likely winner of the Astros vs. Mariners game.
This article offers further insights into Monday's matchup, including best bets and picks.
Astros vs. Mariners prediction: Who will win and cover?
Using trusted machine learning and data, we have simulated the outcome of Monday's MLB game between the Astros and Mariners, forming part of our MLB predictions coverage.
Our independent predictive model gives the Mariners a 61% chance of defeating the Astros.
According to our model, the Astros (+1.5) have a 57% chance of covering the run line, while the over/under total of 7.5 runs has a 52% chance of going over.
Astros vs. Mariners odds [4/13/2026]
We have sourced the best MLB odds in America for this game, which are listed here:
| Bet Type | Astros | Mariners |
|---|---|---|
| Run Line | +1.5 (-137) | -1.5 (+125) |
| Moneyline | +150 | -175 |
| Total | o7.5 (-115) | u7.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Astros vs. Mariners picks and best bet
After matching our predictions against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Run Line | Astros +1.5 | -137 |
| Moneyline | Astros | +150 |
| Total | Over 7.5 | -115 |
According to our MLB best bets, the top play to make on this game is Astros to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Astros vs. Mariners game-day updates and essential details
Monday's MLB matchup between the Mariners and Astros at T-Mobile Park is scheduled to begin at 4:10 PM ET.
- Who: Houston Astros vs. Seattle Mariners
- Date: Monday, April 13, 2026
- Time: 4:10 PM ET/1:10PM PT
- Venue: T-Mobile Park
Conclusion
We predict the Mariners, with a 61% win probability, will likely beat the Astros in Monday's MLB matchup.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.
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