Harvard vs. Yale prediction: Harvard favored to win in college football Week 13, 2025

Yale and Harvard will clash in Week 13 college football action at Yale Bowl on Saturday, starting at 12:00PM ET.

Based on updated simulations, Dimers' proven college football model predicts Harvard as the most likely winner of the Harvard vs. Yale game.

This article offers an expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Harvard vs. Yale prediction: Who will win and cover?

Using trusted machine learning and data, we have simulated the outcome of Harvard vs. Yale 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Harvard a 68% chance of beating Yale. Our predicted final score has Harvard winning 29-22.

According to our model, Yale (+7) has a 53% chance of covering the spread, while the 50.5-point over/under has a 53% chance of staying under.

Harvard vs. Yale odds

We have researched the best College Football odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Harvard vs. Yale picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

According to our best college football bets, the top play to make on this game is Under 50.5 total points.

Harvard vs. Yale game-day updates and essential details

Saturday's college football game between Yale and Harvard at Yale Bowl is scheduled to commence at 12:00PM ET.

• Who: Harvard vs. Yale
• Date: Saturday, November 22, 2025
• Time: 12:00PM ET/9:00AM PT
• Venue: Yale Bowl

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Conclusion

We predict Harvard, with a 68% win probability, will likely beat Yale on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Harvard vs. Yale insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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