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Georgetown vs. Holy Cross prediction: Holy Cross favored to win in college football Week 13, 2025

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Written by Mac Douglass

Get Georgetown vs Holy Cross predictions for college football Saturday.

Georgetown-Holy Cross Predictions and Game Preview.
Georgetown vs. Holy Cross college football gameday prediction for Saturday, November 22, 2025.

Holy Cross will face Georgetown in Week 13 college football action at Fenway Park on Saturday, starting at 4:00PM ET.

Based on the latest simulations, Dimers' proven college football model predicts Holy Cross as the most likely winner of the Georgetown vs. Holy Cross game.

This article offers a closer look at Saturday's matchup, including an expanded look at the predicted score, best bets and picks.

Georgetown vs. Holy Cross prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Georgetown vs. Holy Cross 10,000 times as part of our college football predictions coverage.

Our leading predictive model gives Holy Cross a 61% chance of beating Georgetown. Our predicted final score has Holy Cross winning 24-20.

According to our model, Georgetown (+4.5) has a 52% chance of covering the spread, while the over/under total of 44.5 points has a 51% chance of staying under.

 

Georgetown vs. Holy Cross odds

We have researched the best College Football odds in America for this game, which are listed here:

Bet Type Georgetown Holy Cross
Spread +4.5 (-110) -4.5 (-110)
Moneyline +165 -188
Total o44.5 (-110) u44.5 (-110)

All odds are correct at the time of publication and are subject to change.

Georgetown vs. Holy Cross picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Spread Georgetown +4.5 -110
Moneyline Georgetown +165
Total Under 44.5 -110

According to our college football best bets, the top play to make on this game is Georgetown to win.

 

Georgetown vs. Holy Cross game-day updates and essential details

Saturday's college football action between Holy Cross and Georgetown at Fenway Park is scheduled to start at 4:00PM ET.

  • Who: Georgetown vs. Holy Cross
  • Date: Saturday, November 22, 2025
  • Time: 4:00PM ET/1:00PM PT
  • Venue: Fenway Park

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Conclusion

We predict Holy Cross, with a 61% win probability, will likely beat Georgetown on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Georgetown vs. Holy Cross insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Mac Douglass
Senior Editor

Mac Douglass specializes in NFL previews for the NFC South and NFC East, MLB best bets, Formula 1 race previews, and professional tennis insights. Combining predictive simulations and data-driven sports analysis, Mac provides in-depth content to elevate the betting experience for sports fans.

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