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Daniil Medvedev vs. Frances Tiafoe prediction, odds, picks for ATP Brisbane International 2026

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Written by Dave Garofolo

Get Medvedev vs Tiafoe predictions for ATP Brisbane International.

Daniil Medvedev vs Frances Tiafoe Tennis Prediction.
Our Daniil Medvedev and Frances Tiafoe tennis prediction is based on thousands of simulations of the upcoming match.

Daniil Medvedev will square off with Frances Tiafoe in the round of 16 at the ATP Brisbane event on Tuesday.

Based on the latest simulations, Dimers' proven tennis model projects Daniil Medvedev as the most likely winner of the Medvedev vs. Tiafoe match.

This article offers an expanded analysis of Tuesday's match, including best bets and picks.

Medvedev vs. Tiafoe prediction: Who will win and advance to the quarterfinals?

Using trusted machine learning and data, we have simulated the result of Tuesday's Medvedev-Tiafoe men's singles match 10,000 times as part of our tennis predictions coverage.

Our independent predictive model gives Medvedev a 74% chance of defeating Tiafoe at the ATP Brisbane International tournament.

Additionally, Medvedev has a 70% chance of winning the first set. The simulations also show Medvedev (-3.5) has a 53% chance of covering the games spread, while the under 22.5 games has a 55% chance of hitting, according to our model.

 

Daniil Medvedev vs. Frances Tiafoe odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type Medvedev Tiafoe
Moneyline -297 +255
First Set -250 +200
Game Spread +3.5 (-110) -3.5 (-122)
Total Games o22.5 (-108) u22.5 (-124)

All odds are correct at the time of publication and are subject to change.

Medvedev vs. Tiafoe picks and best bet

After matching our probabilities against the best available odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:

Bet Type Pick Bet Now
Moneyline Medvedev -297
First Set Tiafoe -124

According to our tennis best bets, the top play to make on this match is Daniil Medvedev to win the first set.

Medvedev vs. Tiafoe updates and essential details

The ATP Brisbane International match between Daniil Medvedev and Frances Tiafoe is scheduled to start on Tuesday at 10:10 PM ET.

  • Who: Daniil Medvedev vs. Frances Tiafoe
  • Date: Tuesday, January 6, 2026
  • Approx. Time: 10:10 PM ET/7:10PM PT
  • Tournament: ATP Brisbane, Australia Men's Singles 2026
  • Round: Round of 16

All dates and times in this article are United States Eastern Time unless otherwise noted.

Conclusion

We predict Daniil Medvedev, with a 74% win probability, will likely beat Frances Tiafoe at the ATP Brisbane International tournament.

AI and automation have enhanced this article to quickly deliver accurate Medvedev vs. Tiafoe insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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