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Read Article Daniil Medvedev vs. Flavio Cobolli prediction, odds, picks for ATP Madrid Open 2026
Updated: | First published:
Written by Dave Garofolo, Content Producer
Get Medvedev vs Cobolli predictions for ATP Madrid Open.
Daniil Medvedev will take on Flavio Cobolli in the round of 16 at the ATP Madrid event on Tuesday.
Based on updated simulations, Dimers' advanced tennis model predicts Daniil Medvedev as the most likely winner of the Medvedev vs. Cobolli match.
This article offers further insights into Tuesday's match, including best bets and picks.
Medvedev vs. Cobolli prediction: Who will win and advance to the quarterfinals?
Using trusted machine learning and data analysis, we have simulated the result of Tuesday's Medvedev-Cobolli men's singles match, forming part of our tennis predictions coverage.
Our famous predictive model currently gives Medvedev a 55% chance of winning against Cobolli at the ATP Madrid Open tournament.
Additionally, Medvedev has a 55% chance of winning the first set. The simulations also show Cobolli (+1.5) has a 53% chance of covering the games spread, while the **over/under of 22.5 games has an equal 50-50 chance of hitting, according to our model.
Daniil Medvedev vs. Flavio Cobolli odds
We have sourced the most up-to-date betting odds in America for this match, which are listed here:
| Bet Type | Medvedev | Cobolli |
|---|---|---|
| Moneyline | -120 | +105 |
| First Set | -125 | +100 |
| Game Spread | -1.5 (-110) | +1.5 (-145) |
| Total Games | o22.5 (-126) | u22.5 (-108) |
All odds are correct at the time of publication and are subject to change.
Medvedev vs. Cobolli picks and best bet
After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below:
| Bet Type | Pick | Bet Now |
|---|---|---|
| Moneyline | Medvedev | -120 |
| First Set | Cobolli | -108 |
According to our tennis best bets, the top play to make on this match is Daniil Medvedev to win.
These picks are based on our probabilities matched against the implied probabilities from the sportsbook odds.
Medvedev vs. Cobolli updates and essential details
The ATP Madrid Open match between Daniil Medvedev and Flavio Cobolli is scheduled to begin on Tuesday at 3:00 PM ET.
- Who: Daniil Medvedev vs. Flavio Cobolli
- Date: Tuesday, April 28, 2026
- Approx. Time: 3:00 PM ET/12:00PM PT
- Tournament: ATP Madrid, Spain Men's Singles 2026
- Round: Round of 16
All dates and times mentioned in this article are United States Eastern Time unless otherwise noted.
Conclusion
We predict Daniil Medvedev, with a 55% win probability, will likely beat Flavio Cobolli at the ATP Madrid Open tournament.
Additional tools and information for betting safely can be found in our Responsible Gambling hub.
Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.
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