Colorado State vs. San Diego State prediction: San Diego State favored to win in college football Week 6, 2025

San Diego State and Colorado State will clash in Week 6 college football action at Snapdragon Stadium on Friday, starting at 10:30PM ET.

Based on updated simulation results, Dimers' advanced college football model predicts the San Diego State as the most likely winner of today's game.

For a closer look at Friday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Colorado State vs. San Diego State predictions page.

Colorado State vs. San Diego State prediction: Who will win, cover the spread?

Using innovative machine learning and statistical analysis, we have simulated the result of Colorado State vs. San Diego State 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives San Diego State a 64% chance of beating Colorado State. Our predicted final score has San Diego State winning 24-19.

According to our model, the bookmakers have got it right, and Colorado State and San Diego State each have a 50% chance of covering the spread, while the over/under total of 41.5 points has a 60% chance of staying under.

Colorado State vs. San Diego State odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Colorado State	San Diego State
Spread	+4.5 (-104)	-4.5 (-105)
Moneyline	+175	-190
Total	o41.5 (-105)	u41.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Colorado State vs. San Diego State picks and best bets

Our model's strongest edge in today's Colorado State vs. San Diego State matchup is on the spread.

Our expert predictions, matched against the latest odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Colorado State vs. San Diego State game-day updates and essential details

Friday's college football action between San Diego State and Colorado State at Snapdragon Stadium is scheduled to begin at 10:30PM ET.

• Who: Colorado State vs. San Diego State
• Date: Friday, October 3, 2025
• Time: 10:30PM ET/7:30PM PT
• Venue: Snapdragon Stadium

Dimers' comprehensive preview of Friday's Colorado State vs. San Diego State matchup includes our prediction, picks and the latest betting odds.

Before making any Colorado State vs. San Diego State picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

Conclusion

We predict San Diego State, with a 64% win probability, will likely beat Colorado State on Friday.

AI and automation have enhanced this article to quickly deliver accurate Colorado State vs. San Diego State insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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