College football picks today: Week 11 Thursday best bets include Georgia Southern vs. Appalachian State play [11/6/2025]

Today’s college football picks for November 6, 2025 are here, with Georgia Southern vs. Appalachian State among the top plays identified by our model across Thursday’s college football play.

Dimers’ predictive analytics engine runs 24/7, scanning the latest football odds to uncover genuine betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of college football picks tonight [11/6, updated 7:02PM ET]

Below, you’ll find today’s best college football bets, ranked by edge for Thursday, November 6, 2025.

Georgia Southern ML (+170)

• Edge: 8.1%
• Probability: 45.1%
• Matchup: Georgia Southern vs. Appalachian State (7:30PM ET, Thursday)

Our model has identified value on Georgia Southern to defeat Appalachian State at +170 odds. A 45.1% probability produces an edge of 8.1%, making this the strongest play for today's college football slate.

Georgia Southern +4.5 (-105)

• Edge: 7.8%
• Probability: 59%
• Matchup: Georgia Southern vs. Appalachian State (7:30PM ET, Thursday)

Georgia Southern +4.5 carries a 7.8% edge and a probability of 59% at -105 odds, according to our model.

Georgia Southern vs. Appalachian State over 61.5 points (-108)

• Edge: 5.0%
• Probability: 56.9%
• Matchup: Georgia Southern vs. Appalachian State (7:30PM ET, Thursday)

Georgia Southern vs. Appalachian State over 61.5 points at -108 odds shows a 5.0% edge, supported by a 56.9% probability in simulations.

Morgan State ML (+152)

• Edge: 7.4%
• Probability: 47.1%
• Matchup: Delaware State vs. Morgan State (7:00PM ET, Friday)

A 7.4% edge and 47.1% probability make Morgan State at the moneyline at a value play in the Delaware State vs. Morgan State matchup, per our model.

Georgia Southern vs. Appalachian State over 61.5 points (-108)

• Edge: 5.0%
• Probability: 56.9%
• Matchup: Georgia Southern vs. Appalachian State (7:30PM ET, Thursday)

Georgia Southern vs. Appalachian State over 61.5 points at -108 odds presents a 5.0% edge, with simulations resulting in a probability of 56.9%.

NCAAF best bets summary: Thursday, 11/6/2025

As of 7:02PM ET, here are our top college football bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Georgia Southern vs. Appalachian State	Georgia Southern ML	+170 @ BetMGM	8.1%	45.1%
Georgia Southern vs. Appalachian State	Georgia Southern +4.5	-105 @ DraftKings	7.8%	59%
Georgia Southern vs. Appalachian State	Over 61.5 Points	-108 @ DraftKings	5.0%	56.9%
Delaware State vs. Morgan State	Morgan State ML	+152 @ FanDuel	7.4%	47.1%
Georgia Southern vs. Appalachian State	Over 61.5 Points	-108 @ DraftKings	5.0%	56.9%

List of upcoming college football games to bet on now

• UTSA vs. South Florida (7:30PM ET, Thursday)
• Georgia Southern vs. Appalachian State (7:30PM ET, Thursday)
• Delaware State vs. Morgan State (7:00PM ET, Friday)
• Harvard vs. Columbia (7:00PM ET, Friday)

More college football betting

For further insights into this week's NCAAF action, check out the latest from the Dimers Sports Betting Podcast:

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Conclusion

Our college football best bets are locked and loaded for November 6, 2025, featuring plays such as Georgia Southern ML and Georgia Southern +4.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college football insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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