College football picks today: Saturday's best bets include Gator Bowl play [12/27/2025]

Today’s college football picks for December 27, 2025 are here, with Virginia vs. Missouri and LSU vs. Houston among the top plays identified by our model across Saturday’s college football action.

Dimers’ predictive analytics engine runs 24/7, going over the latest football odds to find legitimate betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of college football picks today [12/27, updated 5:31PM ET]

Below, you’ll find today’s best college football bets, ranked by edge for Saturday, December 27, 2025.

Virginia vs. Missouri under 44.5 points (-115)

• Edge: 8.3%
• Probability: 61.7%
• Matchup: Gator Bowl (7:30PM ET, Saturday)

Our model has identified value on under 44.5 points in Virginia vs. Missouri at -115 odds. A 61.7% probability produces an edge of 8.3%, making this the strongest play for today's college football slate.

LSU vs. Houston under 41.5 points (-105)

• Edge: 5.8%
• Probability: 57%
• Matchup: Texas Bowl (9:15PM ET, Saturday)

LSU vs. Houston under 41.5 points carries a 5.8% edge and a probability of 57% at -105 odds, according to our model.

San Diego State ML (+250)

• Edge: 3.3%
• Probability: 31.9%
• Matchup: New Mexico Bowl (5:45PM ET, Saturday)

San Diego State ML at +250 odds shows a 3.3% edge, supported by a 31.9% probability in simulations.

Missouri -4 (-105)

• Edge: 2.0%
• Probability: 53.2%
• Matchup: Gator Bowl (7:30PM ET, Saturday)

A 2.0% edge and 53.2% probability make Missouri -4 vs. Virginia at a value play in the Virginia vs. Missouri matchup, per our model.

NCAAF best bets summary: Saturday, 12/27/2025

As of 5:31PM ET, here are our top college football bets by edge recommended by our model:

List of upcoming college football games to bet on now

• North Texas vs. San Diego State (5:45PM ET, Saturday)
• Virginia vs. Missouri (7:30PM ET, Saturday)
• LSU vs. Houston (9:15PM ET, Saturday)

AI betting support with Dimebot

Learn how Dimebot uses Dimers’ data to deliver quick answers and insights, helping you make faster, more informed decisions.

Conclusion

Our college football best bets are locked and loaded for December 27, 2025, featuring plays such as under 44.5 points in the Virginia vs. Missouri matchup and under 41.5 points in the LSU vs. Houston matchup. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college football insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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