College football picks today: Week 9 Saturday best bets include two spread plays [10/25/2025]

Today’s college football picks for October 25, 2025 are here, with Tennessee vs. Kentucky among the top plays identified by our model across Saturday’s college football slate.

Dimers’ predictive analytics engine runs 24/7, scanning the latest football odds to uncover genuine betting edges. The result? Data-backed picks that help Dimers Pro members make smarter decisions.

List of college football picks tonight [10/25, updated 7:31PM ET]

Below, you’ll find today’s best football bets, ranked by edge for Saturday, October 25, 2025.

Kentucky +7.5 (-105)

• Edge: 11.2%
• Probability: 62.4%
• Matchup: Tennessee vs. Kentucky (7:45PM ET, Saturday)

Our model has identified value on Kentucky +7.5 at -105 odds. A 62.4% probability produces an edge of 11.2%, making this the strongest play for today's college football slate.

Kentucky ML (+245)

• Edge: 11.1%
• Probability: 40.1%
• Matchup: Tennessee vs. Kentucky (7:45PM ET, Saturday)

Kentucky ML carries a 11.1% edge and a probability of 40.1% at +245 odds, according to our model.

South Dakota State +6.5 (+124)

• Edge: 8.2%
• Probability: 52.9%
• Matchup: North Dakota State vs. South Dakota State (8:00PM ET, Saturday)

South Dakota State +6.5 at +124 odds shows a 8.2% edge, supported by a 52.9% probability in simulations.

South Dakota State ML (+260)

• Edge: 7.7%
• Probability: 35.5%
• Matchup: North Dakota State vs. South Dakota State (8:00PM ET, Saturday)

A 7.7% edge and 35.5% probability make South Dakota State at the moneyline at a value play in the Stanford vs. Hawaii matchup, per our model.

Houston ML (+240)

• Edge: 5.7%
• Probability: 35.1%
• Matchup: Houston vs. Arizona State (8:00PM ET, Saturday)

Houston ML at +240 odds presents a 5.7% edge, with simulations resulting in a probability of 35.1%.

NCAAF best bets summary: Saturday, 10/25/2025

As of 7:31PM ET, here are our top college football bets by edge recommended by our model:

Matchup	Bet	Odds	Edge	Probability
Tennessee vs. Kentucky	Kentucky +7.5	-105 @ BetMGM	11.2%	62.4%
Tennessee vs. Kentucky	Kentucky ML	+245 @ FanDuel	11.1%	40.1%
North Dakota State vs. South Dakota State	South Dakota State +6.5	+124 @ FanDuel	8.2%	52.9%
North Dakota State vs. South Dakota State	South Dakota State ML	+260 @ BetMGM	7.7%	35.5%
Houston vs. Arizona State	Houston ML	+240 @ DraftKings	5.7%	35.1%

List of upcoming college football games to bet on now

• Tennessee vs. Kentucky (7:45PM ET, Saturday)
• Houston vs. Arizona State (8:00PM ET, Saturday)
• North Dakota State vs. South Dakota State (8:00PM ET, Saturday)
• Montana State vs. Cal Poly (8:00PM ET, Saturday)
• Southern Utah vs. Utah Tech (8:00PM ET, Saturday)
• Colorado vs. Utah (10:15PM ET, Saturday)

More college football betting

For further insights into this week's NCAAF action, check out the latest from the Dimers Sports Betting Podcast:

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Conclusion

Our college football best bets are locked and loaded for October 25, 2025, featuring plays such as Kentucky +7.5 and Kentucky ML. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate college football insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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