Guardians vs. Mariners prediction: Seattle favored to win Sunday's MLB matchup [3/29/2026]

The Seattle Mariners will face the Cleveland Guardians in MLB action at T-Mobile Park on Sunday, beginning at 7:20 PM ET.

The Mariners will have Emerson Hancock (0-0, 0.00 ERA) as their starting pitcher, while the Guardians are going with Slade Cecconi (0-0, 0.00 ERA).

Based on updated simulations, Dimers' refined MLB model projects the Mariners as the most likely winner of the Guardians vs. Mariners game.

This article offers further insights into Sunday's matchup, including best bets and picks.

Guardians vs. Mariners prediction: Who will win and cover?

Using powerful machine learning and statistical analysis, we have simulated the result of Sunday's MLB game between the Guardians and Mariners, forming part of our MLB predictions coverage.

Our famous predictive model gives the Mariners a 61% chance of defeating the Guardians.

According to our model, the Guardians (+1.5) have a 57% chance of covering the run line, while the over/under total of 7.5 runs has a 51% chance of staying under.

Guardians vs. Mariners odds [3/29/2026]

We have researched the best MLB odds in America for this game, which are listed here:

All odds are correct at the time of publication and are subject to change.

Guardians vs. Mariners picks and best bet

After matching our predictions against the best current odds, we can reveal our picks for each of the major markets. Plus, find our best bet for the game below: